Results 11 to 20 of about 622,574 (301)
Insulin-Like Growth Factor-1 and Neuroinflammation [PDF]
Frontiers in Aging Neuroscience, 2017 Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia +8 more
doaj +3 more sources
Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection
Cell Death and Disease, 2022 Insulin-like growth factor I (IGF-1) is a neurotrophic factor and is the ligand for insulin-like growth factor 1 receptor (IGF-1R). Reduced expression of IGF-1 has been reported to cause deafness, mental retardation, postnatal growth failure, and ...
Ammaji Rajala +6 more
doaj +3 more sources
Insulin-like growth factor-1 and zinc
Turkish Journal of Hematology, 2008 Nejat Akar
doaj +2 more sources
Insulin-like Growth Factor 1 Signaling in Mammalian Hearing [PDF]
Genes, 2021 Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high-affinity tyrosine kinase receptor (IGF1R), a transmembrane receptor belonging to the insulin receptor family.
Ángela García-Mato +4 more
openaire +4 more sources
Heart Smart Insulin-Like Growth Factor 1 [PDF]
Hypertension, 2012 See related article, pp 680–693 The prevalence of obesity, metabolic syndrome, and type 2 diabetes mellitus, and the associated cardiac pathologies are rising to alarming levels. Conventional medical therapies for the prevention and treatment of cardiomyopathy are less effective in patients with these metabolic disorders, and this is attributed, at ...
Marsh, Susan A, Davidoff, Amy J
openaire +3 more sources
Microgravity, Bone Homeostasis, and Insulin-Like Growth Factor-1
Applied Sciences, 2020 Astronauts at are risk of losing 1.0–1.5% of their bone mass for every month they spend in space despite their adherence to high impact exercise training programs and diets high in nutrients, potassium, calcium, and vitamin D, all designed to preserve ...
John Kelly Smith
doaj +1 more source
Changes in Insulin-like Growth Factor-1 Level in Patients with Sepsis and Septic Shock [PDF]
Korean Journal of Critical Care Medicine, 2016 Background Despite many ongoing, prospective studies on the topic, sepsis still remains one of the main causes of death in hospital. The hormone insulin-like growth factor 1 (IGF-1) has a similar molecular structure to that of insulin.
Sang Hoon Lee +10 more
doaj +1 more source
Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease [PDF]
, 2007 Background: Insulin-like growth factor (IGF)-1 has been implicated in the pathogenesis of Alzheimer's disease ( AD). Methods: We compared the level of circulating total and bioavailable IGF-1, by simultaneous measurements of IGF-1 and IGF binding ...
Bowie, P.C.W +5 more
core +1 more source
Insulin-like growth factor-1 is a negative modulator of glucagon secretion [PDF]
, 2017 Glucagon secretion involves a combination of paracrine, autocrine, hormonal, and autonomic neural mechanisms. Type 2 diabetes often presents impaired glucagon suppression by insulin and glucose.
Andreozzi, F +6 more
core +1 more source
Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]
, 2020 Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter +7 more
core +1 more source