Results 21 to 30 of about 113,487,708 (298)

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Takahashi, Sumio, Takeuchi, Sakae, Kanayama, Munetoshi, Maekawa, Tetsuya   +3 more
core   +1 more source

Insulin-like growth factor 1 and hair growth

Dermatology Online Journal, 1999
Insulin-like growth factor 1 (IGF-1) has been identified as an important growth factor in many biological systems.[1] It shares considerable structural homology with insulin and exerts insulin-like effects on food intake and glucose metabolism. Recently it has been suggested to play a role in regulating cellular proliferation and migration during the ...
Su, Hung-Yi, Hickford, Jonathan G H, Palmer, Barry R, Bickerstaffe, Roy   +3 more
openaire   +4 more sources

Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]

, 2005
Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Mann, Karlheinz, Mann, K., Ghosh, M., Machleidt, W., Machleidt, Werner, Siwanowicz, I., Ghosh, Madhumita, Holak, Tad A., Holak, T., Siwanowicz, Igor, Shanker, Sreejesh, Shanker, S.   +11 more
core   +1 more source

Insulin-Like Growth Factor 1 in Patients with Hypoglycaemia [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1990
Plasma insulin-like growth factor 1 (IGF-1) concentrations were measured in a group of patients with hypoglycaemia due to endogenous hyperinsulinism, and compared with those in a group of patients matched for age and sex with hypoglycaemia and appropriately suppressed insulin levels. Insulin-like growth factor I concentrations were significantly higher
M, Labib, D, Teale, V, Marks
openaire   +2 more sources

Effects of Insulin-Like Growth Factor (IGF-1) in Patients with Sensorineural Hearing Loss

, 2021
OBJECTIVES: (1) To test the effect of local administration of insulin-like growth factor-1 (IGF-1) in patients with sensorineural hearing loss (SNHL). (2) To test the effect of local administration of IGF-1 in patients with ototoxicity.
Varun Jitendra Dave, Kshitij Shah, Manish Prajapati, Joshi, Anagha, Shah, Kshitij, Renuka Bradoo, Dave, Varun Jitendra, Prajapati, Manish, Bradoo, Renuka, Anagha Joshi   +9 more
core   +1 more source

In silico interaction of insulin-like growth factor binding protein 3 with insulin-like growth factor 1

Research in Pharmaceutical Sciences, 2018
Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari, Ali Gheysarzadeh, Karim Mahnam, Rezvan Shahmohammadi, Amir Ansari, Hadi Bakhtyari, Mohammad Reza Mofid   +6 more
doaj   +1 more source

Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]

, 1992
Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg, Guse, Andreas H., Kessler, Ulrike, Funk, Barbara, Gercken, Günther, A. H. Guse, Kiess, Wieland   +6 more
core   +2 more sources

Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]

, 1994
Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
E. Wolf, Eckhard Wolf, Kramer, Rainer, Föll, Jürgen, Gottfried Brem, Brem, Gottfried, Wolf, Eckhard, Jijrgen Fijll, Blum, Werner F., Werner F. Blum, Rainer Kramer   +10 more
core   +2 more sources

Molecular evolution and functional characterization of Drosophila insulin-like peptides [PDF]

, 2010
Multicellular animals match costly activities, such as growth and reproduction, to the environment through nutrient-sensing pathways. The insulin/IGF signaling (IIS) pathway plays key roles in growth, metabolism, stress resistance, reproduction, and ...
Andrews, T Daniel, Partridge, Linda, Grönke, Sebastian, Broughton, Susan, Clarke, David-Francis   +4 more
core   +5 more sources

Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]

, 2013
Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C, Colston, KW, G. Pirianov, K. W. Colston, C. Brosseau, Pirianov, G   +5 more
core   +1 more source