Results 11 to 20 of about 408,308 (200)

Insulin-Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes [PDF]

Journal of Diabetes Research
The insulin-like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems.
Aleksandra Gladych-Macioszek, Katarzyna Ozegowska, Sandra Radzicka-Mularczyk, Rafał Sibiak, Gernot Desoye, Ewa Wender-Ozegowska   +5 more
doaj   +2 more sources

Insulin-like growth factor-II and bioactive proteins containing a part of the E-domain of pro-insulin-like growth factor-II. [PDF]

Biofactors, 2020
AbstractInsulin‐like growth factor (IGF)‐II is considered to function as an important fetal growth factor, which is structurally and functionally related to IGF‐I and proinsulin. At least in vitro, IGF‐II actions are mediated through the IGF‐I receptor and to a lesser extent the insulin receptor.
van Doorn J.
europepmc   +5 more sources

Circulating Insulin-Like Growth Factor II and Colorectal Adenomas* [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2000
Abstract Circulating insulin-like growth factor I (IGF-I) and IGF-binding protein-3 (IGFBP-3) may be risk factors for the development of colorectal cancer. On the other hand, IGF-II and IGFBP-2 are overexpressed in colorectal carcinomas.
Renehan, Andrew G., Painter, John E., O'Halloran, Domhnall, Atkin, Wendy S., Potten, Christopher S., O'Dwyer, Sarah T., Shalet, Stephen M.   +6 more
openaire   +4 more sources

A case of nonislet cell tumor hypoglycemia associated with malignant mesothelioma requiring a multifaceted approach for optimal glycemic control

Clinical Case Reports, 2021
Nonislet tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome characterized by refractory hypoglycemia, which often requires multifaceted therapy.
Mariko Ono, Yuki Maeda, Nobuyuki Koyama, Terumasa Nagase, Yoshiya Katsura, Hiroyuki Nakamura, Kazutetsu Aoshiba   +6 more
doaj   +1 more source

Malignant fibroma presenting as a hypoglycemia and coma in a 45‐year‐old male patient: A case report

Clinical Case Reports, 2022
Solitary fibrous tumors (SFTs) are a rare group of spindle cell neoplasm of submesothelial origin with malignant potential and can present as hypoglycemia secondary to excess secretion of insulin‐like growth factor II (IGF‐II) from the tumor.
Muhammad Hanif, Vikash Jaiswal, Sidra Naz, Nirmit Patel, Nishan Babu Pokhrel, Mounika Reddy Vadiyala   +5 more
doaj   +1 more source

Associations Between IGF-II Gene Polymorphism and Milk Yield Characteristics In Brown Swiss Cattle

Turkish Journal of Agriculture: Food Science and Technology, 2023
This study was carried out on 114 Brown Swiss cattle reared in intensive conditions at Ataturk University Food and Livestock Application and Research Center and at the private cattle farm found in Erzurum province.
Esma Yuca, Sinan Kopuzlu
doaj   +1 more source

Determinants of IGF-II influencing stability, receptor binding and activation

Scientific Reports, 2022
Insulin like growth factor II (IGF-II) is involved in metabolic and mitogenic signalling in mammalian cells and plays important roles in normal fetal development and postnatal growth.
Andrew Blyth, Michael Ortiz, Allanah Merriman, Carlie Delaine, Briony Forbes   +4 more
doaj   +1 more source

Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B [PDF]

, 2013
Insulin and insulin-like growth factors (IGFs) act on tetrameric tyrosine kinase receptors controlling essential functions including growth, metabolism, reproduction and longevity.
Barcos, Lucía Soledad, Coluccio Leskow, Federico, Giordano, Luciana, Giudice, Jimena, Guaimas, Francisco Fernando, Jares, Elizabeth Andrea, Penas Steinhardt, Alberto   +6 more
core   +3 more sources

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II. [PDF]

PLoS ONE, 2011
BACKGROUND: Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function.
Clair L Alvino, Shee Chee Ong, Kerrie A McNeil, Carlie Delaine, Grant W Booker, John C Wallace, Briony E Forbes   +6 more
doaj   +1 more source

Recurrent Severe Hypoglycemia Secondary to Benign Phyllodes Tumour of the Breast

Journal of the ASEAN Federation of Endocrine Societies, 2022
Non-Islet Cell Tumor-induced hypoglycemia (NICTH) secondary to phyllodes tumour is extremely rare but potentially life threatening if not treated promptly.
Hwee Ching Tee, Vijiya Mala Valayatham
doaj   +1 more source