Results 11 to 20 of about 826,191 (386)

Insulin-like growth factor receptors [PDF]

Journal of Cell Science, 1985
ABSTRACT There are two types of insulin-like growth factor (IGF) receptors. The type I receptor generally binds IGF-I more tightly than IGF-II and also interacts weakly with insulin. The type II receptor prefers IGF-II over IGF-I and does not recognize insulin.
S. Peter Nissley, Joyce F. Haskell, Norio Sasaki, Monique A. de Vroede, Matthew M. Rechler   +4 more
openalex   +3 more sources

Animal insulin-like growth factor binding proteins and their biological functions

Veterinární Medicína, 2002
Insulin-like growth factor (IGF-I, IGF-II) action is influenced by until today known eight forms of insulin-like growth factor binding proteins (IGFBPs).
Z. Kostecká, J. Blahovec
doaj   +1 more source

Doxorubicin impairs the insulin-like growth factor-1 system and causes insulin-like growth factor-1 resistance in cardiomyocytes. [PDF]

PLoS ONE, 2015
Insulin-like growth factor-1 (IGF-1) promotes the survival of cardiomyocytes by activating type 1 IGF receptor (IGF-1R). Within the myocardium, IGF-1 action is modulated by IGF binding protein-3 (IGFBP-3), which sequesters IGF-1 away from IGF-1R.
Patrizia Fabbi, Paolo Spallarossa, Silvano Garibaldi, Chiara Barisione, Marzia Mura, Paola Altieri, Barbara Rebesco, Maria Gaia Monti, Marco Canepa, Giorgio Ghigliotti, Claudio Brunelli, Pietro Ameri   +11 more
doaj   +1 more source

Pasireotide for the Medical Management of Feline Hypersomatotropism [PDF]

, 2015
BACKGROUND: Feline hypersomatotropism (HST) is a cause of diabetes mellitus in cats. Pasireotide is a novel multireceptor ligand somatostatin analog that improves biochemical control of humans with HST.
Abraham, Adams, Alt, Appleton, Bhayana, Bruns, Castillo, Church, Colao, Colao, Cuevas-Ramos, Fedele, Fernandez-Rodriguez, Fougner, Golor, Henry, Hofland, Juul, Katznelson, Kvols, Lamb, Lamberts, Maxwell, Meij, Miller, Murray, Myers, Niessen, Niessen, Niessen, Niessen, Petrus, Polska, Rand, Ray, Schmid, Schmid, Sheppard, Slingerland, Sohmiya, Starkey, Stolk, Taboada, Wajchenberg, Zatelli, Zou   +45 more
core   +1 more source

Identifying the Main Factors of Iran's Economic Growth using Growth Accounting Framework [PDF]

European Journal of Business and Management Research, Vol 6 No 5 (2021), 239-245, 2021
This paper aims to present empirical analysis of Iranian economic growth from 1950 to 2018 using data from the World Bank, Madison Data Bank, Statistical Center of Iran, and Central Bank of Iran. The results show that Gross Domestic Product (GDP) per capital increased by 2 percent annually during this time, however this indicator has had a huge ...
arxiv   +1 more source

Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation [PDF]

, 2016
Experimental results for the determination of internalization rates for IGF1-IGF1R, IGF2-IGF1R, IGF2-IGF2R.
Dan Tian, Isaiah Mitchell, Pamela K. Kreeger   +2 more
core   +5 more sources

Cloning and expression of full-length human insulin-like growth factor binding protein 3 (IGFBP3) in the Escherichia coli

Advanced Biomedical Research, 2015
Background: The effect of the growth hormone on target cells is mediated by the insulin-like growth factor 1 (IGF-1). IGF-1 binds to the insulin-like growth factor binding proteins (IGFBPs) in blood and biological fluids.
Emad Khodadadi, Mojtaba Panjepour, Mahdi Abbasian, Zahra Khalili Broujeni, Mohammad Reza Mofid   +4 more
doaj   +1 more source

Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease [PDF]

, 2011
Study identifying an Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease presented at the annual congress of the british toxicology ...
Anne Pryde, David J. Flint, Emma M. Large, Filippi, John N. Plevris, M. Helen Grant, Nakamura, Sokolovic, Yasuoka, Yasuoka   +9 more
core   +1 more source

Insulin-Like Growth Factors

Neurosignals, 1992
The insulin-like growth factors (IGF-I and IGF-II) play important roles in the regulation of growth and metabolism. While the liver is the main source of circulating IGFs, their production by numerous extrahepatic tissues suggests the existence of autocrine and paracrine modes of action in addition to typical endocrine mechanisms.
Joshua Shemer, Michelle McGuinness, Martin L. Adamo, Haim Werner, Derek LeRoith, Fabienne Lanau, Charles T. Roberts, Hisanori Kato, Bethel Stannard, Teresa N. Faria   +9 more
openaire   +3 more sources

IGFBP-2 and -3 co-ordinately regulate IGF1 induced matrix mineralisation of differentiating human dental pulp cells [PDF]

, 2016
Human dental pulp cells (DPCs), which are known to contain a subset of stem cells capable of reforming a dentin and pulp-like complex upon in vivo transplantation, were isolated from third molars of three healthy donors and differentiated to a matrix ...
Aishah Alhodhodi, Andress, Andress, Annunziata, Canalis, Caviedes-Bucheli, Caviedes-Bucheli, Chen, Deirdre Devine, Delany, Durham, Durham, El-Gendy, Feng, Gan, Gotz, Gronthos, Gronthos, Gronthos, Hanaa Alkharobi, Hasanain Alkafaji, James Beattie, Joseph, Kerkis, Kim, Kim, Koch, Le Douarin, Le Douarin, Li, Mori, Mori, Morsczeck, Murphy, Nakashima, Onishi, Palermo, Pintar, Reem El-Gendy, Reichenmiller, Seo, Shi, Sonoyama, Vandomme, Wang, Wong, Xi, Xian, Xue, Yamamoto, Yang, Yousef Hawsawi, Zhang   +52 more
core   +1 more source