Results 21 to 30 of about 826,191 (386)
Research in Pharmaceutical Sciences, 2018 Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari +6 more
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Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism. [PDF]
, 1996 The insulin-like growth factor binding proteins (IGFBPs) are a family of six secreted proteins which bind to and modulate the actions of insulin-like growth factors-I and -II (IGF-I and -II).
James, PL, Rotwein, P, Stewart, CE
core +2 more sources
How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. [PDF]
, 2020 Human type 1 insulin-like growth factor receptor (IGF-1R) signals chiefly in response to the binding of insulin-like growth factor I. Relatively little is known about the role of insulin-like growth factor II signaling via IGF-1R, despite the affinity of
Croll, Tristan I +9 more
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General law of growth and replication. Growth equation and its applications [PDF]
Biophysical Reviews and Letters, 2012 Vol. 7, No. 1-2, p. 71-120, 2012 We present significantly advanced studies of the previously introduced physical growth mechanism and unite it with biochemical growth factors. Obtained results allowed formulating the general growth law which governs growth and evolutional development of all living organisms, their organs and systems.
arxiv +1 more source
Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]
, 2005 Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Andress +15 more
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Insulin-Like Growth Factor Receptor [PDF]
Journal of Thoracic Oncology, 2011 The insulin-like growth factor (IGF) signaling axis plays an essential role in the balance between cellular proliferation and apoptosis. Higher levels of IGF receptor are seen in lung tumor cells than normal tissue. IGF-1 receptor (IGFR-1R) and its ligand IGF-2 is overexpressed in non-small cell lung cancer (NSCLC).
openaire +3 more sources
Neural Regeneration Research, 2023 Skin-derived precursor Schwann cells have been reported to play a protective role in the central nervous system. The neuroprotective effects of skin-derived precursor Schwann cells may be attributable to the release of growth factors that nourish host ...
Hai-Ying Zhang +7 more
doaj +1 more source
The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency [PDF]
, 2016 The visceral adiposity index, based on anthropometric and metabolic parameters, has been shown to be related to adipose tissue function and insulin sensitivity.
Ciresi, A. +3 more
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The Insulin‐Like Growth Factor System [PDF]
Journal of Diabetes Research, 2003 The insulin‐like growth factor (IGF) system in ubiquitous and plays a role in every tissue of the body. It is comprised of ligands, receptors and binding proteins, each with specific functions. While it plays an essential role in embryonic and post‐natal development, the IGF system is also important in normal adult physiology.
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Archives of Medical Science, 2020 Introduction Uterine fibroids (UFs) are benign tumors of the female reproductive system originating from the smooth muscle of the uterus. Currently, progesterone is known to play a key role in the differentiation of the myometrial tissue to form UFs and ...
Michał Ciebiera +7 more
doaj +1 more source