Results 191 to 200 of about 418,496 (299)

Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is important for intracellular targeting of lysosomal enzymes.

, 1993
H.J. Chen, Johannes Remmler, James C. Delaney, Donald J. Messner, Peter Lobel   +4 more
openalex   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Insulin-like growth factor II mRNA binding protein 3 is highly expressed in primary diffuse large B-cell lymphoma of the CNS. [PDF]

J Clin Exp Hematop
Odani K, Fujimoto M, Fujii H, Saka M, Mizoguchi K, Hirata M, Sakurai T, Takeuchi Y, Minamiguchi S, Arakawa Y, Haga H.   +10 more
europepmc   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Insulin-like growth factor II mRNA-binding protein 3 promotes cell proliferation, migration and invasion in human glioblastoma. [PDF]

Onco Targets Ther, 2019
Wu C, Ma H, Qi G, Chen F, Chu J.
europepmc   +1 more source

Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6

, 1993
Leon A. Bach, Susan Hsieh, Katsu-ichi Sakano, Hiroyuki Fujiwara, James F. Perdue, Matthew M. Rechler   +5 more
openalex   +1 more source

Mannose-6-Phosphate Enhances Cross-Linking Efficiency between Insulin-Like Growth Factor-II (IGF-II) and IGF-II/Mannose-6-Phosphate Receptors in Membranes* [PDF]

, 1991
Richard G. MacDonald
openalex   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Insulin-Like Growth Factor II Targets the mTOR Pathway to Reverse Autism-Like Phenotypes in Mice. [PDF]

J Neurosci, 2018
Steinmetz AB, Stern SA, Kohtz AS, Descalzi G, Alberini CM.   +4 more
europepmc   +1 more source

Insulin-like growth factor-II as a prognostic factor in pulmonary adenocarcinoma [PDF]

, 1996
Iwao Takanami, Tetsuo Imamuma, Toshinori Hashizume, Keiichi Kikuchi, Yasuki Yamamoto, Tatsuya Yamamoto, Susumu Kodaira   +6 more
openalex   +1 more source