Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases. [PDF]
Wang Y +3 more
europepmc +1 more source
Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor [PDF]
Bartolomé Burguera +7 more
openalex +1 more source
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Enhancement of memories by systemic administration of insulin-like growth factor II. [PDF]
Stern SA +3 more
europepmc +1 more source
Tyrosine hydroxylase and insulin‐like growth factor II but not insulin are adjacent in the teleost species barramundi, Lates calcarifer [PDF]
C. Collet, Judith M. Candy, V. R. Sara
openalex +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
Upregulation of insulin-like growth factor II mRNA-binding protein 3 (IMP3) has negative prognostic impact on early invasive (pT1) adenocarcinoma of the esophagus. [PDF]
Plum PS +11 more
europepmc +1 more source
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler +7 more
wiley +1 more source
A Hypoglycemia-inducing Giant Borderline Phyllodes Tumor Secreting High-molecular-weight Insulin-Like Growth Factor II: Immunohistochemistry and a Western Blot Analysis. [PDF]
Hikichi M +7 more
europepmc +1 more source

