Results 261 to 270 of about 463,657 (378)

Progestin and Antiprogestin Differentially Regulate the Expression of Insulin-like Growth Factors (IGF-I and IGF-II) Messenger Ribonucleic Acid in Human Endometrial Stromal Cells1 [PDF]

, 1995
Jiaguo Gao, Hui Zhu, Jei Fan, James Mazella, Linda Tseng   +4 more
openalex   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Down-Regulation of the Serum Stimulatory Components of the Insulin-like Growth Factor (IGF) System (IGF-I, IGF-II, IGF Binding Protein [BP]-3, and IGFBP-5) in Age-Related (Type II) Femoral Neck Osteoporosis

, 1999
Steven Boonen, Subburaman Mohan, Jan Dequeker, Jeroen Aerssens, Dirk Vanderschueren, Geert Verbeke, Paul Broos, Roger Bouillon, David J. Baylink   +8 more
openalex   +1 more source

The Molecular Basis of Amino Acids Sensing

Advanced Science, EarlyView.
Amino acids are essential as protein building blocks and signaling molecules, enabling metabolic regulation. Cells sense amino acid levels to control protein synthesis, maintain homeostasis, and adapt to nutritional changes. This review explores recent advances in amino acid sensing mechanisms across organisms, highlighting their roles in cellular ...
Cong Jiang, Xiao Tan, Jiali Jin, Ping Wang   +3 more
wiley   +1 more source

Insulin-Like Growth Factor II mRNA-Binding Protein 3 Expression Correlates with Poor Prognosis in Acral Lentiginous Melanoma. [PDF]

PLoS One, 2016
Sheen YS, Liao YH, Lin MH, Chiu HC, Jee SH, Liau JY, Chang YL, Chu CY.   +7 more
europepmc   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability. [PDF]

Mol Cell Biol, 2015
Wang Y, Buggia-Prévot V, Zavorka ME, Bleackley RC, MacDonald RG, Thinakaran G, Kar S.   +6 more
europepmc   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

Advanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou   +11 more
wiley   +1 more source

Insulin-like growth factor-II in adipocyte regulation: depot-specific actions suggest a potential role limiting excess visceral adiposity.

Am J Physiol Endocrinol Metab, 2018
Alfares MN, Perks CM, Hamilton-Shield JP, Holly JMP.   +3 more
europepmc   +1 more source

Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation

, 1997
Satyabrata Kar, David Seto, Sylvain Doré, UK Hanisch, Rémi Quirion   +4 more
openalex   +1 more source