Results 21 to 30 of about 463,657 (378)
Primary structure of human insulin‐like growth factor II [PDF]
FEBS Letters, 1978 René E. Humbel, Ernst Rinderknecht
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Insulin-like growth factor-II in the cycle of life [PDF]
Biomedical Reviews, 1996 The insulin-like growth factors (IGF-I and IGF-II) play important roles in growth and development. They are structurally homologous to proinsulin and can interact with the type I and type II IGF receptors and, to a lesser extent, the insulin receptor.
van Buul-Offers, Sylvia C.
openaire +4 more sources
Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. [PDF]
J Biol Chem, 2016 Insulin and insulin-like growth factors I and II are closely related protein hormones. Their distinct evolution has resulted in different yet overlapping biological functions with insulin becoming a key regulator of metabolism, whereas insulin-like ...
Hexnerová R +13 more
europepmc +3 more sources
Definitions, 2020 Insulin-like growth factor II (180 aa, ~20 kDa) is encoded by the human IGF2 gene. This protein plays a role in cellular growth, development, and mitogenesis.
semanticscholar +1 more source
Clinical Case Reports, 2021 Nonislet tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome characterized by refractory hypoglycemia, which often requires multifaceted therapy.
Mariko Ono +6 more
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How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. [PDF]
, 2020 Human type 1 insulin-like growth factor receptor (IGF-1R) signals chiefly in response to the binding of insulin-like growth factor I. Relatively little is known about the role of insulin-like growth factor II signaling via IGF-1R, despite the affinity of
Croll, Tristan I +9 more
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Malignant fibroma presenting as a hypoglycemia and coma in a 45‐year‐old male patient: A case report
Clinical Case Reports, 2022 Solitary fibrous tumors (SFTs) are a rare group of spindle cell neoplasm of submesothelial origin with malignant potential and can present as hypoglycemia secondary to excess secretion of insulin‐like growth factor II (IGF‐II) from the tumor.
Muhammad Hanif +5 more
doaj +1 more source
Associations Between IGF-II Gene Polymorphism and Milk Yield Characteristics In Brown Swiss Cattle
Turkish Journal of Agriculture: Food Science and Technology, 2023 This study was carried out on 114 Brown Swiss cattle reared in intensive conditions at Ataturk University Food and Livestock Application and Research Center and at the private cattle farm found in Erzurum province.
Esma Yuca, Sinan Kopuzlu
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Determinants of IGF-II influencing stability, receptor binding and activation
Scientific Reports, 2022 Insulin like growth factor II (IGF-II) is involved in metabolic and mitogenic signalling in mammalian cells and plays important roles in normal fetal development and postnatal growth.
Andrew Blyth +4 more
doaj +1 more source
Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis [PDF]
, 2004 The Type I insulin-like growth factor receptor is a physiological receptor for insulin-like growth factor II (IGF-II). To characterize the molecular basis of the receptor's ligand binding properties, we have examined the effects of alanine mutations of ...
Baker +17 more
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