Results 11 to 20 of about 22,902,059 (175)

Blood feeding and insulin-like peptide 3 stimulate proliferation of hemocytes in the mosquito Aedes aegypti. [PDF]

PLoS Pathogens, 2011
All vector mosquito species must feed on the blood of a vertebrate host to produce eggs. Multiple cycles of blood feeding also promote frequent contacts with hosts, which enhance the risk of exposure to infectious agents and disease transmission.
Julio Castillo, Mark R Brown, Michael R Strand   +2 more
doaj   +4 more sources

Associations of serum C-peptide and insulin-like growth factor binding proteins-3 with breast cancer deaths.

PLoS ONE, 2020
C-peptide is usually considered as a marker of insulin secretion and has no physiological function. This study aimed to assess the association between serum C-peptide level as independent risk factor and breast cancer and explored the possible underlying
PinYu Cui, Yuan Chen, Nuremaguli Waili, YaXing Li, CuiLing Ma, Ying Li   +5 more
doaj   +4 more sources

Molecular evolution and functional characterization of Drosophila insulin-like peptides [PDF]

, 2010
Multicellular animals match costly activities, such as growth and reproduction, to the environment through nutrient-sensing pathways. The insulin/IGF signaling (IIS) pathway plays key roles in growth, metabolism, stress resistance, reproduction, and ...
Andrews, T Daniel, Partridge, Linda, Grönke, Sebastian, Broughton, Susan, Clarke, David-Francis   +4 more
core   +5 more sources

Insulin-like peptide 3 stimulates hemocytes to proliferate in anautogenous and facultatively autogenous mosquitoes.

J Exp Biol, 2022
ABSTRACTMost mosquito species are anautogenous, which means they must blood feed on a vertebrate host to produce eggs, while a few are autogenous and can produce eggs without blood feeding. Egg formation is best understood in the anautogenous mosquito Aedes aegypti, where insulin-like peptides (ILPs), ovary ecdysteroidogenic hormone (OEH) and 20 ...
Martinson EO, Chen K, Valzania L, Brown MR, Strand MR.   +4 more
europepmc   +3 more sources

Relaxin and insulin-like peptide 3 in the musculoskeletal system: from bench to bedside. [PDF]

Br J Pharmacol, 2017
Skeletal muscles and bones form a joined functional unit sharing a complex mechanical, biochemical and hormonal crosstalk. A number of factors, including sex hormones, physiologically regulate the musculoskeletal system. Striking gender differences in muscle and bone mass, and function are mainly caused by distinct actions exerted by oestrogens and ...
Ferlin A, Ferlin A, De Toni L, Sandri M, Foresta C.   +4 more
europepmc   +6 more sources

The binding and activation of the glucagon-like peptide-1 receptor by exendin-4 [PDF]

, 2010
Background and purpose Exendin-4 (EX4) has the same physiological properties as glucagon-like peptide-1 (7-36)amide (GLP-1). EX4 has 50% identity with GLP-1, with an extra nine amino acids at its C-terminus.
Nasr, Elsayed Mohammed Nasr
core   +6 more sources

Diverse functions of insulin-like 3 peptide [PDF]

Journal of Endocrinology, 2020
Insulin-like 3 peptide (INSL3) is a member of the insulin-like peptide superfamily and is the only known physiological ligand of relaxin family peptide receptor 2 (RXFP2), a G protein-coupled receptor (GPCR). In mammals, INSL3 is primarily produced both in testicular Leydig cells and in ovarian theca cells, but circulating levels of the hormone are ...
Maria, Esteban-Lopez, Alexander I, Agoulnik   +1 more
openaire   +2 more sources

GREAT/LGR8 Is the Only Receptor for Insulin-Like 3 Peptide [PDF]

Molecular Endocrinology, 2003
During male development testes descend from their embryonic intraabdominal position into the scrotum. Two genes, encoding the insulin-like 3 peptide (INSL3) and the GREAT/LGR8 G protein-coupled receptor, control the differentiation of gubernaculum, the caudal genitoinguinal ligament critical for testicular descent.
Bogatcheva, N. V., Truong, A., Feng, S., Engel, Wolfgang, Adham, Ibrahim M., Agoulnik, A. I.   +5 more
openaire   +3 more sources

Insulin-Like Peptides and Cross-Talk With Other Factors in the Regulation of Insect Metabolism

Frontiers in Physiology, 2021
The insulin-like peptide (ILP) and insulin-like growth factor (IGF) signalling pathways play a crucial role in the regulation of metabolism, growth and development, fecundity, stress resistance, and lifespan.
Szymon Chowański, Karolina Walkowiak-Nowicka, Magdalena Winkiel, Pawel Marciniak, Arkadiusz Urbański, Arkadiusz Urbański, Joanna Pacholska-Bogalska   +6 more
doaj   +1 more source

Associations of insulin and insulin-like growth factors with physical performance in old age in the boyd orr and caerphilly studies. [PDF]

, 2012
OBJECTIVE: Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition.
Gallacher, J, Holly, JM, Martin, RM, Birnie, K, Gunnell, D, Ben-Shlomo, Y, Ebrahim, S, Bayer, A   +7 more
core   +5 more sources