Results 101 to 110 of about 815 (149)

Therapeutic targeting of insulin-regulated aminopeptidase: heads and tails?

, 2007
Insulin-regulated aminopeptidase, IRAP, is an abundant protein that was initially cloned from a rat epididymal fat pad cDNA library as a marker protein for specialized vesicles containing the insulin-responsive glucose transporter GLUT4, wherein it is ...
AL Albiston (15886124), GR Peck (15878378), R Fernando (11166417), HR Yeatman (15886127), S Ye (7645880), SY Chai (15886130)   +5 more
core  

Role of insulin-regulated aminopeptidase as potential biomarker in insulin resistant polycystic ovary syndrome patients. [PDF]

Arch Endocrinol Metab
Köse O, Gök K, Köse E, Gözükara SI, Tüten A, Bostancı MS.   +5 more
europepmc   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross-Presentation. [PDF]

Eur J Immunol
Senni A, Grumbach L, Ceccacci S, Frechin M, Goudin N, Guerrera IC, Bertocci B, van Endert P.   +7 more
europepmc   +1 more source

Integrated analysis of the adipocyte plasma membrane proteome reveals KCC1 and PIT2 as novel insulin-responsive transporters. [PDF]

J Biol Chem
Zhang Y, Cooke KC, Scavuzzo J, Cutler HB, Madsen S, Kearney AL, Conway OJ, Hawkins BL, Menon D, Humphrey SJ, Koumanov F, Stöckli J, Geddes TA, Fazakerley DJ, Diaz-Vegas A, Burchfield JG, James DE.   +16 more
europepmc   +1 more source

Quantum Mechanics/Molecular Mechanics Simulations Distinguish Insulin-Regulated Aminopeptidase Substrate (Oxytocin) and Inhibitor (Angiotensin IV) and Reveal Determinants of Activity and Inhibition. [PDF]

J Chem Inf Model
Hanževački M, Twidale RM, Lang EJM, Gerrard W, Wright DW, Stojevic V, Mulholland AJ.   +6 more
europepmc   +1 more source

Discovery of Novel Allosteric Inhibitor Hits for Insulin-Regulated Aminopeptidase Provides Insights on Enzymatic Mechanism. [PDF]

ACS Omega
Georgaki G, Koutroumpa NM, Lagarias P, Afantitis A, Papakyriakou A, Stratikos E.   +5 more
europepmc   +1 more source

Deep learning-driven proteomics analysis for gene annotation in the renin-angiotensin system. [PDF]

Eur J Pharmacol
Eivazi M, Hosseini K, Alipanahi S, Xia H, Restivo L, Patel A, Gozali M, Ebrahimi T, Scarborough A, Tarhriz V, Lazartigues E.   +10 more
europepmc   +1 more source

GLUT4 Trafficking and Storage Vesicles: Molecular Architecture, Regulatory Networks, and Their Disruption in Insulin Resistance. [PDF]

Int J Mol Sci
Drobiova H, Alhamar G, Ahmad R, Al-Mulla F, Al Madhoun A.   +4 more
europepmc   +1 more source

Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells. [PDF]

Int J Mol Sci
Stam F, Bjurling S, Nylander E, Håkansson EO, Barlow N, Gising J, Larhed M, Odell LR, Grönbladh A, Hallberg M.   +9 more
europepmc   +1 more source

Sex-Specific Exosome Cargo Reveals Potential New Mechanisms of Salt-Sensitive Hypertension. [PDF]

Hypertension
Tarhriz V, Xia H, Patel A, Eivazi M, Scarborough A, Miao K, Mir H, Abkhooie L, Mauvais-Jarvis F, Lazartigues E.   +9 more
europepmc   +1 more source