Results 71 to 80 of about 131,508 (302)
Proteomic Analysis Reveals a Mitochondrial Remodeling of βTC3 Cells in Response to Nanotopography
Frontiers in Cell and Developmental Biology, 2020 Recently, using cluster-assembled zirconia substrates with tailored roughness produced by supersonic cluster beam deposition, we demonstrated that β cells can sense nanoscale features of the substrate and can translate these stimuli into a ...
Elisa Maffioli +15 more
doaj +1 more source
Reprogramming—Evolving Path to Functional Surrogate β-Cells
Cells, 2022 Numerous cell sources are being explored to replenish functional β-cell mass since the proof-of -concept for cell therapy of diabetes was laid down by transplantation of islets. Many of these cell sources have been shown to possess a degree of plasticity
Eric Kalo, Scott Read, Golo Ahlenstiel
doaj +1 more source
FUNCTIONAL EXAMINATION OF MICROENCAPSULATED BIOENGINEERED INSULIN-SECRETING BETA-CELLS
, 2001 Clonal insulin-secreting BRIN-BD11 cells engineered by electrofusion were encapsulated inside natrium alginate beads and cultured in RPMI 1640 culture media.
McClenaghan, N H +7 more
core +1 more source
Insulin secretion by a transplantable rat islet cell tumour [PDF]
Diabetologia, 1981 Investigation of the subcellular and molecular components of insulin secretion has been made difficult by the small quantities of material available. The recent development of a transplantable rat islet cell tumour of high insulin content and state of differentiation suggested a system more amenable to analysis.
A M, Sopwith +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Recent Advances in Obesity-induced Inflammation and Insulin Resistance.
Frontiers in Endocrinology, 2013 It has been demonstrated in rodents and humans that chronic inflammation characterized by macrophage infiltration occurs mainly in adipose tissue or liver during obesity, in which activation of immune cells is closely associated with insulin sensitivity.
Sanshiro eTateya +3 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
, 2007 Pulsatile insulin output, paralleled by oscillations in intracellular Ca(2+), reflect oscillating metabolism within beta-cells in response to secretory fuels.
Heart, Emma +3 more
core +1 more source
Electrokinetic measurements of membrane capacitance and conductance for pancreatic -cells [PDF]
, 2005 Author Posting. © The Authors, 2005. This is the author's version of the work. It is posted here by permission of IEE for personal use, not for redistribution.
Jakubek, L. M. +10 more
core +1 more source
Characterization of glucose transport in an insulin-secreting cell line [PDF]
Biochemical Journal, 1987 The rat insulinoma-derived RINm5F cell line retains many differentiated functions of islet beta-cells. However, it fails to recognize glucose as an insulin secretagogue in the physiological concentration range. With this cell line, glucose-transport kinetics were investigated, by using a double-label technique with the non-metabolizable glucose ...
M E, Trautmann, C B, Wollheim
openaire +2 more sources