Results 251 to 260 of about 4,469,131 (358)

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

Advanced Science, EarlyView.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh, Albert Kallon Koroma, Rajeev Kumar Pandey, Yongfang Wang, Jinnan Cheng, Philipp Haas, Mahyar Aghapour, Linda Krug, Adelheid Hainzl, Meinhard Wlaschek, Pallab Maity, Karin Scharffetter‐Kochanek   +11 more
wiley   +1 more source

Association between shift work and insulin resistance in women: Implications for metabolic health. [PDF]

PLoS One
Choi YJ, Cho SH, Leigh JH, Jeong SH.
europepmc   +1 more source

Novel Clinical Evidence of an Association between Homocysteine and Insulin Resistance in Patients with Hypothyroidism or Subclinical Hypothyroidism

, 2015
Ning Yang, Zhi Yao, Miao Li, Jia Liu, Xia Gao, Hui Fan, Yanjin Hu, Heng Zhang, Yuan Xu, Aijuan Qu, Guang Wang   +10 more
openalex   +2 more sources

Circadian clocks and insulin resistance

Nature Reviews Endocrinology, 2018
D. J. Stenvers, F. Scheer, P. Schrauwen, S. L. la Fleur, A. Kalsbeek   +4 more
semanticscholar   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Endoplasmic reticulum stress contributes to insulin resistance in Hashimoto's thyroiditis. [PDF]

Endocr Connect
Zhou Q, Zhang LY, Gao XL, Zou CC, Liu H.
europepmc   +1 more source

Arginine 16 Glycine Polymorphism inβ2-Adrenergic Receptor Gene Is Associated with Obesity, Hyperlipidemia, Hyperleptinemia, and Insulin Resistance in Saudis [PDF]

, 2012
Maha H. Daghestani, Arjumand S. Warsy, Mazin H. Daghestani, Ali Al‐Odaib, Abdelmoneim Eldali, Nadia A. Aleisa, Sawsan A. Omer, Zeinab Hassan   +7 more
openalex   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum. [PDF]

Front Endocrinol (Lausanne)
Prosperi S, Chiarelli F.
europepmc   +1 more source

Knockout of TRPC6 promotes insulin resistance and exacerbates glomerular injury in Akita mice

, 2019
Liming Wang, Jae‐Hyung Chang, Anne F. Buckley, Robert F. Spurney   +3 more
openalex   +2 more sources