Results 251 to 260 of about 4,252,621 (405)

Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion

Advanced Science, EarlyView.
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang, Mei Huang, Ling Liu, Fang Yang, Chen He, Yu‐Chen Sun, Yu‐Rui Jiao, Xiang Tang, Jing Hou, Kai‐Xuan Chen, Wen‐Zhen He, Jie Wei, Hui‐Ling Chen, Xia Li, Chao Zeng, Guang‐Hua Lei, Chang‐Jun Li   +16 more
wiley   +1 more source

Trends in Prevalence of Insulin Resistance Among Nondiabetic/Nonprediabetic Adolescents, 1999-2020. [PDF]

Pediatr Diabetes
Zhao D, Wang L, Jiao X, Shi C, Luo Z, Chen Y, Zhang Y.   +6 more
europepmc   +1 more source

Production of Inhibitor of Insulin-Receptor Tyrosine Kinase in Fibroblasts From Patient With Insulin Resistance and NIDDM [PDF]

, 1991
Paolo Sbraccia, Patricia A. Goodman, Betty A. Maddux, Kwok-Ying Wong, Y-D.I. Chen, Gerald M. Reaven, Ira D. Goldfine   +6 more
openalex   +1 more source

Adipocytes Promote Cisplatin Resistance through Secreting A1BG and Regulating NAMPT/PARP1 Axis‐Mediated DNA Repair in Osteosarcoma

Advanced Science, EarlyView.
The proposed working model for how adipocytes participate in cisplatin resistance in osteosarcoma. The adipocytes secret A1BG and stabilize NAMPT, leading to increased NAD⁺ levels and subsequent increased PARP1‐mediated DNA repair, resulting in cisplatin resistance in osteosarcoma finally.
Yonghui Liang, Zhaohui Li, Lina Tang, Zhen Pan, Xiang Fei, Chen Tan, Aina He, Qingcheng Yang, Dongdong Cheng   +8 more
wiley   +1 more source

How much insulin resistance in polycystic ovary syndrome? Comparison of HOMA-IR and insulin resistance (Belfiore) index models

Archives of Medical Science, 2019
Krzysztof C. Lewandowski, Elżbieta Skowrońska-Jóźwiak, Katarzyna Łukasiak, Katarzyna Gałuszko, Aleksandra Dukowicz, Magdalena Cedro, Andrzej Lewiński   +6 more
doaj   +1 more source

Plasma endotrophin levels correlate with insulin resistance in people with obesity. [PDF]

J Clin Invest
Smith GI, Klein S.
europepmc   +1 more source

Insulin resistance, insulin, proinsulin, and ambulatory blood pressure in type II diabetes. [PDF]

, 1994
Jonathan Pinkney, Vidya Mohamed‐Ali, A. E. Denver, C Foster, Mike Sampson, John Yudkin   +5 more
openalex   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

Exploring the TyG Index and the Homeostasis Model Assessment of Insulin Resistance as Insulin Resistance Markers: Implications for Fibromyalgia Management and Understanding-A Narrative Review. [PDF]

Diagnostics (Basel)
Samavarchitehrani A, Mercantepe F, Behnoush AH, Klisic A.   +3 more
europepmc   +1 more source

Non-esterified fatty acids do not contribute to insulin resistance in persons at increased risk of developing Type 2 (non-insulin-dependent) diabetes mellitus [PDF]

, 1991
Johan G. Eriksson, Carola Saloranta, E. Wid�n, Agneta Ekstrand, A. Franssila-Kallunki, Camilla Schalin, Per‐Henrik Groop   +6 more
openalex   +1 more source