Results 21 to 30 of about 4,110,467 (359)
Clinical analysis of insulin resistance in liver cirrhosis patients
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Objective·To investigate the insulin resistance in liver cirrhosis patients.Methods·Patients with liver cirrhosis from Xinhua Hospital,Shanghai Jiao Tong University School of Medicine in 2013‒2017 were retrospectively assessed.
SHI Cuicui +4 more
doaj +1 more source
Role of Insulin Resistance in MAFLD
International Journal of Molecular Sciences, 2021 Many studies have reported that metabolic dysfunction is closely involved in the complex mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), which has prompted a movement to consider renaming NAFLD as metabolic dysfunction ...
Yoshitaka Sakurai +3 more
semanticscholar +1 more source
Obesity and Cardiovascular Risk: Variations in Visfatin Gene Can Modify the Obesity Associated Cardiovascular Risk. Results from the Segovia Population Based-Study. Spain. [PDF]
PLoS ONE, 2016 OBJECTIVES:Our aim was to investigate if genetic variations in the visfatin gene (SNPs rs7789066/ rs11977021/rs4730153) could modify the cardiovascular-risk (CV-risk) despite the metabolic phenotype (obesity and glucose tolerance).
María Teresa Martínez Larrad +6 more
doaj +1 more source
Myths about Insulin Resistance: Tribute to Gerald Reaven [PDF]
Endocrinology and Metabolism, 2019 Gerald Reaven was often called the “father of insulin resistance.” On the 1-year anniversary of his death in 2018, we challenge three myths associated with insulin resistance: metformin improves insulin resistance; measurement of waist circumference ...
Sun H. Kim, Fahim Abbasi
doaj +1 more source
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model
Frontiers in Endocrinology, 2022 Insulin resistance (IR) plays a critical role in cardiovascular diseases and metabolic diseases. In this study, we identified the downregulation of DMRT2 in adipose tissues from insulin-resistant subjects through bioinformatics analysis and in an insulin-
Jing Tao +11 more
doaj +1 more source
A small amount of dietary carbohydrate can promote the HFD-induced insulin resistance to a maximal level. [PDF]
PLoS ONE, 2014 Both dietary fat and carbohydrates (Carbs) may play important roles in the development of insulin resistance. The main goal of this study was to further define the roles for fat and dietary carbs in insulin resistance.
Shuang Mei +10 more
doaj +1 more source
Regulation of Insulin Clearance by Non-Esterified Fatty Acids
Biomedicines, 2022 Insulin stores lipid in adipocytes and prevents lipolysis and the release of non-esterified fatty acids (NEFA). Excessive release of NEFA during sustained energy supply and increase in abdominal adiposity trigger systemic insulin resistance, including in
Sonia M. Najjar +8 more
doaj +1 more source
Mechanisms of Insulin Action and Insulin Resistance.
Physiological Reviews, 2018 The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of research into insulin action and resistance has issued. In the intervening century, some discoveries have matured, coalescing into solid and fertile ground for ...
Max C. Petersen, G. Shulman
semanticscholar +1 more source
Assessment of Insulin Secretion and Insulin Resistance in Human
Diabetes & Metabolism Journal, 2021 The impaired insulin secretion and increased insulin resistance (or decreased insulin sensitivity) play a major role in the pathogenesis of all types of diabetes mellitus (DM).
S. Park, J. Gautier, S. Chon
semanticscholar +1 more source