Obesity and Cardiovascular Risk: Variations in Visfatin Gene Can Modify the Obesity Associated Cardiovascular Risk. Results from the Segovia Population Based-Study. Spain. [PDF]
PLoS ONE, 2016 OBJECTIVES:Our aim was to investigate if genetic variations in the visfatin gene (SNPs rs7789066/ rs11977021/rs4730153) could modify the cardiovascular-risk (CV-risk) despite the metabolic phenotype (obesity and glucose tolerance).
María Teresa Martínez Larrad +6 more
doaj +1 more source
Clinical analysis of insulin resistance in liver cirrhosis patients
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Objective·To investigate the insulin resistance in liver cirrhosis patients.Methods·Patients with liver cirrhosis from Xinhua Hospital,Shanghai Jiao Tong University School of Medicine in 2013‒2017 were retrospectively assessed.
SHI Cuicui +4 more
doaj +1 more source
The Effect of a Maternal Mediterranean Diet in Pregnancy on Insulin Resistance is Moderated by Maternal Negative Affect. [PDF]
, 2020 There is inconsistent evidence that healthy dietary interventions can effectively mitigate the risk of adverse outcomes associated with elevated insulin resistance in pregnancy, suggesting that other moderating factors may be at play.
Buss, Claudia +3 more
core +1 more source
Myths about Insulin Resistance: Tribute to Gerald Reaven [PDF]
Endocrinology and Metabolism, 2019 Gerald Reaven was often called the “father of insulin resistance.” On the 1-year anniversary of his death in 2018, we challenge three myths associated with insulin resistance: metformin improves insulin resistance; measurement of waist circumference ...
Sun H. Kim, Fahim Abbasi
doaj +1 more source
A small amount of dietary carbohydrate can promote the HFD-induced insulin resistance to a maximal level. [PDF]
PLoS ONE, 2014 Both dietary fat and carbohydrates (Carbs) may play important roles in the development of insulin resistance. The main goal of this study was to further define the roles for fat and dietary carbs in insulin resistance.
Shuang Mei +10 more
doaj +1 more source
Mangosteen Extract Shows a Potent Insulin Sensitizing Effect in Obese Female Patients: A Prospective Randomized Controlled Pilot Study. [PDF]
, 2018 There is a widely acknowledged association between insulin resistance and obesity/type 2 diabetes (T2DM), and insulin sensitizing treatments have proved effective in preventing diabetes and inducing weight loss.
Addessi, E +11 more
core +2 more sources
Analysis of factors associated with insulin resistance in young women: A cross-sectional study
Clinical Nutrition Open Science, 2023 Summary: Background & aims: Impaired glucose tolerance in young women may lead to the future development of gestational diabetes mellitus and/or type 2 diabetes mellitus.
Isaki Hanamura +6 more
doaj +1 more source
Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action? [PDF]
, 2015 Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging.
LaBarge, Samuel +2 more
core +2 more sources
Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. [PDF]
, 2015 Defective hepatic insulin receptor (IR) signalling is a pathogenic manifestation of metabolic disorders including obesity and diabetes. The endo/lysosomal trafficking system may coordinate insulin action and nutrient homeostasis by endocytosis of IR and ...
Burnol, Anne-Françoise +7 more
core +1 more source