Results 21 to 30 of about 3,853,066 (390)
Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
Frontiers in Physiology, 2020 Obesity is one of the major health burdens of the 21st century as it contributes to the growing prevalence of its related comorbidities, including insulin resistance and type 2 diabetes.
Federica Zatterale +6 more
semanticscholar +1 more source
Journal of Clinical Investigation, 2003 Insulin resistance arises from the inability of insulin to act normally in regulating nutrient metabolism in peripheral tissues. Increasing evidence from human population studies and animal research has established correlative as well as causative links ...
Haiyan Xu +10 more
semanticscholar +1 more source
Metabolic Inflammation and Insulin Resistance in Obesity
Circulation Research, 2020 Supplemental Digital Content is available in the text. Obesity is becoming an epidemic in the United States and worldwide and increases risk for many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular disease.
Huaizhu Wu, C. Ballantyne
semanticscholar +1 more source
The prevalence of the metabolic syndrome in Portugal: the PORMETS study
BMC Public Health, 2017 Background The PORMETS study was designed to estimate the prevalence of metabolic syndrome and its determinants in the overall and administrative regions of the Portuguese mainland.
Luís Raposo +3 more
doaj +1 more source
Obesity, Insulin Resistance, and Type 2 Diabetes: Associations and Therapeutic Implications
Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2020 Obesity is a triggering factor for diabetes associated with insulin resistance. In individuals who are obese, higher amounts of non-esterified fatty acids, glycerol, hormones, and pro-inflammatory cytokines that could participate in the development of ...
Yohannes Tsegyie Wondmkun
semanticscholar +1 more source
Obesity, Bioactive Lipids, and Adipose Tissue Inflammation in Insulin Resistance
Nutrients, 2020 Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. The exact mechanism by which adipose tissue induces insulin resistance is still unclear.
Iwona Kojta +2 more
semanticscholar +1 more source
Mechanisms of Insulin Action and Insulin Resistance.
Physiological Reviews, 2018 The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of research into insulin action and resistance has issued. In the intervening century, some discoveries have matured, coalescing into solid and fertile ground for ...
Max C. Petersen, G. Shulman
semanticscholar +1 more source
Association between insulin resistance and the development of cardiovascular disease
Cardiovascular Diabetology, 2018 For many years, cardiovascular disease (CVD) has been the leading cause of death around the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid profiles and insulin resistance.
V. Ormazábal +5 more
semanticscholar +1 more source
Post-operative insulin resistance
Сахарный диабет, 2017 Post-operative insulin resistance (IR) is a recognised marker of surgical stress. However, the reasons underlying post-operative IR and its clinical value are still unclear.
Irina Aleksandrovna Tarasova +2 more
doaj +1 more source
Annals of Agricultural and Environmental Medicine, 2020 Introduction Insulin resistance is becoming an increasingly widespread problem worldwide. For its determination indirect indices of insulin resistance or insulin sensitivity have used. Those indices based on simultaneous measurements of blood glucose and
Sylwia Płaczkowska +3 more
doaj +1 more source