Results 181 to 190 of about 271,085 (312)

Imeglimin and DPP-4 inhibitors: A promising therapeutic strategy for type 2 diabetes individuals with reduced insulin secretion. [PDF]

Diabetes Obes Metab
Hamamoto Y, Usui R.
europepmc   +1 more source

Insulin secretion from pancreatic islets: Effect of growth hormone and related proteins [PDF]

, 1978
B. A. LARSON, Tim Williams, U.J. Lewis, W. P. VANDERLAAN   +3 more
openalex   +1 more source

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

Maternal and umbilical cord serum lipids in gestational diabetes predict offspring insulin secretion and resistance at the age of nine years. [PDF]

Metabolomics
Huhtala M, Rönnemaa T, Tertti K, Niinikoski H, Paavilainen E.   +4 more
europepmc   +1 more source

Histamine and insulin dose-response studies of gastric secretion in Indian control subjects and patients with duodenal ulcer in the Ganges delta [PDF]

, 1978
K.N. Jalan, Dilip Mahalanabis, T K Maitra, Shriya Agarwal   +3 more
openalex   +1 more source

Large‐Scale Bioprinting of Human Epiblast‐Like Models Featuring Disc‐Shaped Morphogenesis and Gastrulation Events

Advanced Science, EarlyView.
Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo, Liheng Luo, Ling Wang, Shanshan Yang, Hongan Ren, Shaojun Liang, Xiaoyu Wang, Yijun Su, Leqian Yu, Xiaoyue Wang, Mingen Xu, Rui Yao   +11 more
wiley   +1 more source

Molten‐Salt‐Mediated Synthesis of Atomic Manganese/Cobalt Catalysts on Bioceramic Microparticles for Catalytic Anti‐Osteoarthritis Treatments

Advanced Science, EarlyView.
Microparticle‐based antioxidants capable of scavenging multiple reactive oxygen species (ROS) have been developed. When retained within the articular cavity of osteoarthritic mice, Mn‐ or Co‐AKT‐MPs protect the inherent homeostasis between cartilage anabolism and catabolism, and inhibit synovial inflammation.
Ronghui Deng, Zining Zhang, Aijun Wu, Chaoqin Shu, Shitang Song, Fuzhen Yuan, Zijie Xu, Meng Yang, Jing Ye, Yifan Song, Yufang Zhu, Jia‐Kuo Yu   +11 more
wiley   +1 more source

Betagenin ameliorates diabetes by inducing insulin secretion and β-cell proliferation. [PDF]

J Biol Chem
Yokoo T, Watanabe K, Iida K, Nakachi Y, Suzuki H, Shimano H, Takashima S, Okazaki Y, Yamada N, Toyoshima H.   +9 more
europepmc   +1 more source

Effect of free fatty acids and amino acids on glucagon and insulin secretions in normal and diabetic ducks [PDF]

, 1978
F Laurent, P. Mialhe
openalex   +1 more source

BRD4 Signaling Maintains the Differentiated State of β Cells

Advanced Science, EarlyView.
The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu, Guang Liu, Jia Song, Yujing Sun, Mengmeng Yang, Hualin Liu, Hongkai Zhao, Jiamu Chen, Qincheng Qiao, Siyue Li, Chenglong Yu, Jingru Qu, Ying Zou, Tixiao Wang, Jidong Liu, Lei Zhao, Huihui Tian, Tao Huang, Manna Zhang, Li Chen, Ruxing Zhao, Yuanyuan Du, Xinguo Hou   +22 more
wiley   +1 more source