Results 211 to 220 of about 458,144 (260)
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Insulin Secretion in Kwashiorkor
The Journal of Clinical Endocrinology & Metabolism, 1972ABSTRACT Basal plasma insulin levels were normal in kwashiorkor, but their response to oral glucose was impaired. As a result of the impaired insulin secretion, the glucose tolerance was abnormal and there was no reduction in plasma α-amino nitrogen levels.
Kamala S. Jaya Rao, N. Raghuramulu
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American Journal of Physiology-Endocrinology and Metabolism, 2003
Glucose tolerance progressively declines with age, and there is a high prevalence of type 2 diabetes and postchallenge hyperglycemia in the older population. Age-related glucose intolerance in humans is often accompanied by insulin resistance, but circulating insulin levels are similar to those of younger people. Under some conditions of hyperglycemic
Jeffrey B. Halter, Annette M. Chang
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Glucose tolerance progressively declines with age, and there is a high prevalence of type 2 diabetes and postchallenge hyperglycemia in the older population. Age-related glucose intolerance in humans is often accompanied by insulin resistance, but circulating insulin levels are similar to those of younger people. Under some conditions of hyperglycemic
Jeffrey B. Halter, Annette M. Chang
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Somatostatin and insulin secretion
Metabolism, 1978Abstract The inhibitory effect of somatostatin was first demonstrated in in vitro studies in rat pituitary cell cultures. Thus, initially, its action on the release of pituitary hormones in man and animals was the main focus of interest. While investigating the effect of somatostatin on growth hormone release we, as well as other groups, made the ...
Rolf Luft, Per-Eric Lins, Suad Efendic
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The cytoskeleton and insulin secretion
Diabetes/Metabolism Reviews, 1986One of the central, unresolved problems in our understanding of insulin secretion is the way in which stimulus recognition and its associated metabolic events are translated into the mechanical processes of insulin-storage granule movement and extrusion from the cells by exocytosis. In the present article we have examined the structural organization of
M. Tyhurst, S. L. Howell
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New England Journal of Medicine, 1967
ALTHOUGH hyperinsulinemia has been well established in obese subjects1 , 2 only some demonstrate abnormalities of glucose tolerance. It has been suggested that the ability of the obese subject to maintain normal glucose tolerance is a function of B-cell reserve, implying that insulin secretory rates and plasma insulin levels would be higher in obese ...
Roy F. Roddam +3 more
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ALTHOUGH hyperinsulinemia has been well established in obese subjects1 , 2 only some demonstrate abnormalities of glucose tolerance. It has been suggested that the ability of the obese subject to maintain normal glucose tolerance is a function of B-cell reserve, implying that insulin secretory rates and plasma insulin levels would be higher in obese ...
Roy F. Roddam +3 more
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Biosynthesis and secretion of insulin
British Medical Bulletin, 1989The mechanisms involved in the biosynthesis, storage and secretion of insulin in the normal pancreatic B-cell have been the subject of intensive investigation during the last twenty years. As a result of this activity a relatively clear picture has emerged about the basic processes involved, and increasing information is available of their regulation ...
G St J Bird, S L Howell
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Insulin Secretion in Acromegaly
The Journal of Clinical Endocrinology & Metabolism, 1970ABSTRACT A comparative study of insulin release was made in 9 acromegalic and 39 normal subjects who had normal fasting plasma glucoses. Both hyperglycemic (increase of plasma glucose of at least 25 mg/100 ml) and nonhyperglycemic stimuli were used. Those producing hyperglycemia included a 100 g oral glucose tolerance test and a glucose-protein meal ...
S. Edwin Fineberg +3 more
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Hypothermia and Insulin Secretion
Endocrinology, 1970The effect of decreased body temperature on insulin secretion was studied using the isolated perfused rat pancreas. It was found that hypothermia directly inhibits insulin release and that there exists a direct relationship between tissue temperature and total quantity of insulin released (in response to either glucose or tolbutamide stimulation).
Donald L. Curry, Katherine P. Curry
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Colchicine and Insulin Secretion in Man
Diabetes, 1981The present study is aimed at investigating the effect of acute and chronic colchicine administration on insulin secretion in humans. Acute insulin response to glucose (0.33 g/kg) was significantly decreased by colchicine (3 mg i.v.). In fact, this response (mean change 2–10 min insulin) was 44 ± 8 μU/ml before and 32 ± 6 μU/ml after colchicine ...
GIUGLIANO, Dario +6 more
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