Results 31 to 40 of about 543,808 (360)
Metabolites, 2021 Insulin secretion is widely thought to be maximally stimulated in glucose concentrations of 16.7-to-30 mM (300-to-540 mg/dL). However, insulin secretion is seldom tested in hyperglycemia exceeding these levels despite the Guinness World Record being 147 ...
Katherine M. Gerber +5 more
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A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion
Molecular Metabolism, 2020 Objectives: Glucose-stimulated insulin secretion is a critical function in the regulation of glucose homeostasis, and its deregulation is associated with the development of type 2 diabetes.
Dassine Berdous +7 more
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Parathyroid localization [PDF]
, 1986 Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B. +7 more
core +1 more source
Acta Scientiarum: Biological Sciences, 2013 Activation of β2 adrenergic receptors by catecholamine or catecholamine-mimetic substances may enhance insulin secretion. We herein investigated KCl- and nutrient-stimulated insulin secretion in pancreatic islets isolated from β2 knockout (β2KO) mice ...
Anderson Carlos Marçal +5 more
doaj +1 more source
Glucose metabolism and oscillatory behavior of pancreatic islets [PDF]
, 2005 A variety of oscillations are observed in pancreatic islets.We establish a model, incorporating two oscillatory systems of different time scales: One is the well-known bursting model in pancreatic beta-cells and the other is the glucose-insulin feedback ...
A. L. Hodgkin +19 more
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Experimental Biology and Medicine, 1995 Aging in mammals has often been associated with decreased insulin secretion and a subsequent deterioration in the ability to maintain glucose homeostasis. However, recent studies have demonstrated that factors such as disease, obesity, and physical activity more closely reflect diminished insulin secretion rather than aging per se. Thus, the purpose of
M C, Coordt, R C, Ruhe, R B, McDonald
openaire +2 more sources
Islet isolation assessment in man and large animals [PDF]
, 1990 Recent progress in islet isolation from the pancreas of large mammals including man, accentuated the need for the development of precise and reproducible techniques to assess islet yield.
Alejandro, R +25 more
core +1 more source
Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]
, 2020 Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D. +7 more
core +2 more sources
Rosuvastatin Treatment Affects Both Basal and Glucose-Induced Insulin Secretion in INS-1 832/13 Cells. [PDF]
PLoS ONE, 2016 Rosuvastatin is a member of the statin family. Like the other statins it is prescribed to lower cholesterol levels and thereby reduce the risk of cardiovascular events.
Vishal A Salunkhe +3 more
doaj +1 more source
Hypoglycin stimulates insulin secretion [PDF]
Diabetologia, 1977 Hypoglycin A(0.01--1.0 mmol/l) stimulated insulin release from pieces of rabbit pancreas in vitro in the presence or absence of extracellular glucose. The relevance of this finding to the hypoglycaemia of Jamaican vomiting sickness is discussed.
R D, Milner, P K, Wirdnam
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