Results 41 to 50 of about 34,184 (259)

Malignant insulinoma [PDF]

open access: yesOrvosi Hetilap, 2011
Authors present the history of a 56-year-old man who was evaluated for recurrent epigastrial pain. Clinical investigation revealed a 4-cm tumor in the head of the pancreas and a solitary liver metastasis. Pathological examination of the surgically excised pancreatic tumor indicated a moderately differentiated neuroendocrine carcinoma and Ki-67 ...
Miklós, Tóth   +5 more
openaire   +2 more sources

Light‐Mediated Insulin and Amylin Secretion: Influence of Irradiation Parameters in Optogenetically Modified Mouse‐Pancreatic β Cells

open access: yesJournal of Biophotonics, EarlyView.
This study demonstrates variation in photo‐induced secretion of insulin and amylin from Channelrhodopsin‐2 expressing MIN6 cells under different irradiation conditions. For the first time, an alteration in the relative ratio of amylin: insulin is observed with varying irradiation conditions.
Nidhi Maharwal   +3 more
wiley   +1 more source

A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]

open access: yes, 2011
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi   +13 more
core   +1 more source

Pancreatic insulinoma causing hypoglycemic episodes

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Background: Insulinoma typically has non-specific neuroglycopenic symptoms. It is a neuroendocrine tumor of the pancreas, and leads to recurring hypoglycemic attacks stemming from insulin hypersecretion.
Moaffaq Mahdi   +3 more
doaj   +1 more source

Youngest known case of a pancreatic perivascular epithelioid cell tumor

open access: yesJPGN Reports, EarlyView.
Abstract Perivascular epithelioid cell tumors (PEComas) are a rare type of mesenchymal tumor that can arise in any part of the body. As of 2024, 37 cases of pancreatic PEComas had been reported in the literature with patients ranging in age from 17 to 74 years old.
Laura Gilligan   +5 more
wiley   +1 more source

The treatment of hyperinsulinemic hypoglycaemia in adults: an update [PDF]

open access: yes, 2016
Treatment of hyperinsulinemic hypoglycaemia (HH) is challenging due to the rarity of this condition and the difficulty of differential diagnosis.
A. Colao   +6 more
core   +1 more source

Effects of Genistein on Inflammasome Induced Pancreatic β‐Cell Apoptosis by Dexamethasone

open access: yesMolecular Nutrition &Food Research, EarlyView.
The possible mechanism of genistein‐mediated protection against dexamethasone‐induced pancreatic β‐cell apoptosis. Genistein decreases the activation of IRE‐1α, resulting in the reduction of sXBP1, JNK, TXNIP, NLRP3, and IL‐1β expression. Genistein inhibits dexamethasone‐induced pancreatic β‐cell apoptosis.
Nattinee Jitprawet   +4 more
wiley   +1 more source

A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo [PDF]

open access: yes, 2015
SCOPUS: ar.jinfo:eu-repo/semantics ...
Beyaert, Rudi   +6 more
core   +2 more sources

Hipoglucemia e insulinoma

open access: yesRevista Mexicana de Endocrinología, Metabolismo y Nutrición, 2022
La hipoglucemia persistente causada por un insulinoma es una patología poco frecuente que requiere un diagnóstico bioquímico y localización regional del tumor ante la sospecha para un tratamiento adecuado.
Isabel Pulgar-Sedó   +3 more
doaj   +1 more source

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