Results 41 to 50 of about 30,427 (262)
Accidental exposure to glimepiride from adulterated medication resulting in severe hypoglycaemia
Endocrinology, Diabetes & Metabolism Case Reports, 2022 Sulphonylureas are insulinotropic and are not only useful in patients with diabetes but also act in non-diabetic individuals where hypoglycaemia and hyperinsulinism mimic insulinoma.
Annabelle G Hayes +2 more
doaj +1 more source
Clinical characteristics and treatment outcomes of patients with insulinoma-a single center's experience of 76 cases over a 10-year period. [PDF]
HeliyonObjective: Insulinoma is a rare pancreatic neuroendocrine neoplasm caused by pancreatic beta cell tumor or beta cell proliferation resulting in excessive insulin secretion.
Li W, Cheng Y, Ma Q, Wu Z, Wang Z.
europepmc +2 more sources
Successful medical management of insulinoma with diazoxide for 27 years
Endocrinology, Diabetes & Metabolism Case Reports, 2020 Summary Despite improvements in localisation techniques and surgical advances, some patients with insulinoma will not be cured by surgery or may not be suitable for surgery. Medical management with diazoxide is an option for such cases.
Annabelle M. Warren +2 more
semanticscholar +1 more source
British Journal of Surgery, 2006 Abstract Background Insulinomas are rare tumours. Their clinical presentation, localization techniques and operative management were reviewed. Methods An electronic search of the Medline, Embase and Cochrane databases was undertaken ...
Kevin C. Conlon, O N Tucker, Paul Crotty
openaire +3 more sources
Endocrinology, Diabetes & Metabolism Case Reports, 2022 Acanthosis nigricans (AN) is a common dermatosis associated with hyperinsulinemia and insulin resistance. However, AN has been rarely reported in patients with insulinoma, a state of persistent hyperinsulinemia. We present a case of metastatic insulinoma,
Jenny S W Yun +3 more
doaj +1 more source
Insulinoma in childhood. [PDF]
Archives of Disease in Childhood, 1969 Hypoglycaemia is an important cause of cerebral damage in childhood. While much attention has recently been directed to its detection and treatment in the neonatal period, in later childhood the diagnosis is often delayed. There are many possible causes of hypoglycaemia in childhood, but in only a minority of cases is a precise diagnosis made, the ...
P.H.W. Rayner, A. Gourevitch, J. R. Mann
openaire +3 more sources
Exendin‐4 analogs in insulinoma theranostics
Journal of labelled compounds & radiopharmaceuticals, 2019 Insulinomas, neuroendocrine tumors arising from pancreatic beta cells, often show overexpression of the glucagon‐like peptide‐1 receptor. Therefore, imaging with glucagon‐like peptide analog exendin‐4 can be used for diagnosis and preoperative ...
Tom.J.P. Jansen +7 more
semanticscholar +1 more source
Insulinoma Causing Prolonged Hypoglycaemic Coma [PDF]
Journal of Clinical and Diagnostic Research, 2016 Insulinoma is a rare pancreatic endocrine tumour with an incidence of four cases per million per year. A recurrent episode of fasting hypoglycaemia is the most common manifestation of these tumours.
Prabhat Kumar +4 more
doaj +1 more source
Advanced Science, EarlyView.In islet β cells, LGR4 binds with Rspondin to activate the Wnt‐β‐catenin‐Ccnd1 axis, leading to a subsequent increase in cell proliferation. On the other hand, LGR4 also binds with RANKL, thus suppressing the phosphorylation of p44/p42 MAPK and p65 NF‐κB and subsequent cell apoptosis.
Chao Luo +8 more
wiley +1 more source
Duodenal neuroendocrine tumours masquerading as peptic duodenitis, crushed lymphoid aggregates and prominent Brunner glands: some diagnostic pitfalls. [PDF]
HistopathologyHistopathology, Volume 87, Issue 3, Page 478-480, September 2025.
Hasson L, Karamchandani DM.
europepmc +2 more sources