Results 41 to 50 of about 34,487 (256)

A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo [PDF]

open access: yes, 2015
SCOPUS: ar.jinfo:eu-repo/semantics ...
Beyaert, Rudi   +6 more
core   +2 more sources

Acanthosis nigricans in a patient with metastatic insulinoma post peptide receptor radionuclide therapy

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2022
Acanthosis nigricans (AN) is a common dermatosis associated with hyperinsulinemia and insulin resistance. However, AN has been rarely reported in patients with insulinoma, a state of persistent hyperinsulinemia. We present a case of metastatic insulinoma,
Jenny S W Yun   +3 more
doaj   +1 more source

Purification of alpha-toxin from Staphylococcus aureus and application to cell permeabilization [PDF]

open access: yes, 1987
Crude alpha-toxin was produced by Staphylococcus aureus, strain Wood 46. The amount of exotoxin was monitored during growth and all subsequent purification steps by determination of its hemolytic activity against rabbit erythrocytes.
Ahnert-Hilger   +16 more
core   +1 more source

Insulinoma Causing Prolonged Hypoglycaemic Coma [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Insulinoma is a rare pancreatic endocrine tumour with an incidence of four cases per million per year. A recurrent episode of fasting hypoglycaemia is the most common manifestation of these tumours.
Prabhat Kumar   +4 more
doaj   +1 more source

A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]

open access: yes, 2011
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi   +13 more
core   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

open access: yesAdvanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou   +3 more
wiley   +1 more source

Glucose Management during Insulinoma Resection Using Real-Time Subcutaneous Continuous Glucose Monitoring

open access: yesCase Reports in Anesthesiology, 2018
Insulinoma is a rare neuroendocrine tumor that causes hypoglycemia due to unregulated insulin secretion. Blood glucose management during insulinoma resection is therefore challenging.
Yuki Sugiyama   +8 more
doaj   +1 more source

The treatment of hyperinsulinemic hypoglycaemia in adults: an update [PDF]

open access: yes, 2016
Treatment of hyperinsulinemic hypoglycaemia (HH) is challenging due to the rarity of this condition and the difficulty of differential diagnosis.
A. Colao   +6 more
core   +1 more source

An Accessible Platform to Quantify Oxygen Diffusion in Cell‐Laden Hydrogels and Its Application to Alginate‐Immobilized Pancreatic Beta Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
A simple setup to measure oxygen diffusion coefficients was developed using equipment accessible to most wet laboratories. Gels that appeared softer and had lower loss moduli correlated with higher oxygen diffusion coefficients. Dimensionless number analyses using the Thiele Modulus and effectiveness factors were predictive of viability profiles within
Hamid Ebrahimi Orimi   +6 more
wiley   +1 more source

Light‐Mediated Insulin and Amylin Secretion: Influence of Irradiation Parameters in Optogenetically Modified Mouse‐Pancreatic β Cells

open access: yesJournal of Biophotonics, EarlyView.
This study demonstrates variation in photo‐induced secretion of insulin and amylin from Channelrhodopsin‐2 expressing MIN6 cells under different irradiation conditions. For the first time, an alteration in the relative ratio of amylin: insulin is observed with varying irradiation conditions.
Nidhi Maharwal   +3 more
wiley   +1 more source

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