Results 41 to 50 of about 19,209 (213)

Establishing the performance and acceptability of dried blood spot sampling to screen for islet‐specific autoantibodies

Diabetic Medicine, EarlyView.
This comprehensive validation and acceptability study shows dried blood spot sampling can be used as an alternative to serum for use with the 3‐screen assay for population type 1 diabetes autoantibody screening and appears acceptable to parents and stakeholders.
Siân E. Faustini, Lauren M. Quinn, Madeeha Hoque, Siobhan Young, Christopher Bentley, Hin‐Fai Kwok, Timothy Plant, Ian Litchfield, Felicity Boardman, Sheila M. Greenfield, Parth Narendran, Alex G. Richter   +11 more
wiley   +1 more source

Hipoglucemia e insulinoma

Revista Mexicana de Endocrinología, Metabolismo y Nutrición, 2022
La hipoglucemia persistente causada por un insulinoma es una patología poco frecuente que requiere un diagnóstico bioquímico y localización regional del tumor ante la sospecha para un tratamiento adecuado.
Isabel Pulgar-Sedó, Elizabeth Salsavilca, Dioni Gárate-Chirinos, Juan C. Lizarzaburu-Robles   +3 more
doaj   +1 more source

Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio, Anette‐Gabriele Ziegler   +1 more
wiley   +1 more source

INSULINOMA MALIGNO

Revista de la Facultad de Medicina Humana, 2017
El insulinoma es el tumor neuroendocrino del páncreas más frecuente. Se presenta el caso de un paciente de 54 años de edad. La sintomatología conocida por la disminución severa de la glicemia en el sistema nervioso central, el diagnostico se basó en la evidencia de hipoglicemia, asociado a niveles elevados de insulina.
Herrera-Favian, Pedro Roberto, Flores-Delgado, César Alejandro, Hererra-Fernandez, Roy   +2 more
openaire   +4 more sources

Case Report: Hypoglycemia Due to Metastatic Insulinoma in Insulin-Dependent Type 2 Diabetes Successfully Treated With 177 Lu-DOTATATE

Frontiers in Endocrinology, 2022
We describe a 96-year-old man with insulin-dependent type 2 diabetes mellitus who, despite insulin cessation, presented with recurrent hypoglycemia associated with confirmed inappropriate endogenous hyperinsulinemia.
Shejil Kumar, Mariah Melek, Peter Rohl
doaj   +1 more source

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu, Juyun Zhang, Zhu Lin, Xubiao Meng   +3 more
wiley   +1 more source

Insulinoma apresentando-se como crise convulsiva: relato de caso Insulinoma presenting as seizure: case report

Arquivos de Neuro-Psiquiatria, 2005
O insulinoma é doença rara que cursa com sintomas episódicos neuroglicopênicos e/ou adrenérgicos. Descrevemos o caso de uma paciente de 36 anos, que estava sendo tratada por crises convulsivas parciais complexas há 4 anos sem melhora do quadro ...
Carlos Alexandre Twardowschy, Silmara Aparecida de Oliveira Leite, Tatiana Yukie Outi, Michelle Totti Dykyj   +3 more
doaj   +1 more source

Prognostic value of clinical parameters and exosomal lncRNA NEAT1_1 in MEN1‐related non‐functioning pancreatic neuroendocrine tumors

Journal of Neuroendocrinology, EarlyView.
Abstract Non‐functioning pancreatic neuroendocrine tumors (NF‐pNETs) significantly contribute to the premature death of multiple endocrine neoplasia type 1 (MEN1) patients. Reliable prognostic markers are not yet available. MicroRNAs (miRNA) and long‐non‐coding (lnc) RNAs, transported by extracellular vesicles, are emerging as new prognostic tools ...
Jerena Manoharan, Max Albers, Natalia Khizanishvili, Norman Krasser‐Gercke, Maxime Schmitt, Ioannis Mintziras, Sabine Wächter, Anja Rinke, Yutong Gao, Jörg W. Bartsch, Moritz Jesinghaus, Pietro Di Fazio, Detlef K. Bartsch   +12 more
wiley   +1 more source

Insulinoma: presentación neuro psiquiátrica, caso clínico y revisión de la literatura

Revista Médica Clínica Las Condes, 2022
Resumen: Antecedentes: el insulinoma es un tumor infrecuente que desencadena cuadros de hipoglicemia manifestados por los clásicos síntomas vegetativos y neuroglucopénicos.
Luis Ángel Rodríguez, Franco M. Nazario   +1 more
doaj  

Pancreatic neuroendocrine tumors in children and adolescents—Data from the German MET studies (1997–2023)

Journal of Neuroendocrinology, EarlyView.
Abstract Pancreatic neuroendocrine tumors (panNETs) are rare pediatric malignancies with age‐specific clinical and biological features. Data on their presentation, management, and outcomes remain limited. This retrospective study analyzed 28 pediatric panNET cases from the German Malignant Endocrine Tumor (MET) Registry enrolled between 1997 and 2024 ...
Katharina Karges, Marina Kunstreich, Ulrich‐Frank Pape, Jörg Fuchs, Christian Vokuhl, Michael Abele, Dominik T. Schneider, Ines B. Brecht, Constantin Lapa, Michael C. Frühwald, Peter Vorwerk, Antje Redlich, Michaela Kuhlen   +12 more
wiley   +1 more source