Results 41 to 50 of about 14,705 (155)

Case Report: Diazoxide-induced diabetic ketoacidosis in a patient with insulinoma

Frontiers in Endocrinology
Definitive management of insulinoma is challenging as curative surgery is associated with a considerable risk of morbidity and mortality. The successful long-term use of diazoxide for patients diagnosed with insulinoma has been described, but rarely, the
Run Ting Chin, Jolene Jiayu Kiew, Khek Yu Ho, Doddabele S. Deepak   +3 more
doaj   +1 more source

Glucose Management during Insulinoma Resection Using Real-Time Subcutaneous Continuous Glucose Monitoring

Case Reports in Anesthesiology, 2018
Insulinoma is a rare neuroendocrine tumor that causes hypoglycemia due to unregulated insulin secretion. Blood glucose management during insulinoma resection is therefore challenging.
Yuki Sugiyama, Chiaki Kiuchi, Maiko Suzuki, Yuki Maruyama, Ryo Wakabayashi, Yasunari Ohno, Shugo Takahata, Takumi Shibazaki, Mikito Kawamata   +8 more
doaj   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Pancreatic insulinoma causing hypoglycemic episodes

Journal of Pediatric Surgery Case Reports, 2020
Background: Insulinoma typically has non-specific neuroglycopenic symptoms. It is a neuroendocrine tumor of the pancreas, and leads to recurring hypoglycemic attacks stemming from insulin hypersecretion.
Moaffaq Mahdi, Bassel Almehman, Safi Nassan, Soliman Binyahib   +3 more
doaj   +1 more source

Steroidogenic Factor 1 (SF1) Immunohistochemical Stain Is Sensitive and Specific for the Cytopathologic Identification of Intrapancreatic Ectopic Splenic Tissue

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Accessory spleens result from failure of splenic fusion during development and are occasionally located in the pancreatic tail, radiographically appearing as solid or solid/cystic lesions. Fine needle aspiration (FNA) easily identifies accessory spleens in most samples based on architecture and using CD8 to highlight splenic ...
Adeyinka Akinsanya, Jessica L. Muldoon, Mohamed Mustafa, Bin Yang, Hector Mesa, Omer Saeed   +5 more
wiley   +1 more source

Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications

Exploration, EarlyView.
Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu, Yi Li, Hulin Long, Yijia Wu, Ningwei Sun, Shun Li, Yiyao Liu, Huiqi Xie, Ji Bao   +8 more
wiley   +1 more source

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma

International Journal of Cancer, EarlyView.
What's New? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang, Ken Yamaguchi, Kohei Hamada, Yuko Hosoe, Yuka Mise, Sachiko Kitamura, Zhihong Liu, Hairong Wei, Zhenhai Gao, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Rin Mizuno, Taito Miyamoto, Junzo Hamanishi, Masaki Mandai   +15 more
wiley   +1 more source

Diagnostic value of ASVS for insulinoma localization: A systematic review and meta-analysis.

PLoS ONE, 2019
BACKGROUND:Previous studies on the diagnostic value of arterial calcium stimulation with hepatic venous sampling (ASVS) for the localization of insulinoma have reported inconsistent results.
Hao Wang, Ying Ba, Qian Xing, Run-Ce Cai
doaj   +1 more source

Hipoglucemia e insulinoma

Revista Mexicana de Endocrinología, Metabolismo y Nutrición, 2022
La hipoglucemia persistente causada por un insulinoma es una patología poco frecuente que requiere un diagnóstico bioquímico y localización regional del tumor ante la sospecha para un tratamiento adecuado.
Isabel Pulgar-Sedó, Elizabeth Salsavilca, Dioni Gárate-Chirinos, Juan C. Lizarzaburu-Robles   +3 more
doaj   +1 more source