Results 41 to 50 of about 10,095,518 (284)

Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes : salicylate alleviates this stress [PDF]

, 2010
Recent findings indicate that endoplasmic reticulum (ER) stress is significantly increased in adipose tissue of obese human subjects and is critical to the initiation and integration of pathways of inflammation and insulin action.
Saif Alhusaini, Harte, A., McGee, K., Gyanendra Tripathi, Kumar, Sudhesh, Tripathi, Gyanendra, Sudhesh Kumar, Alhusaini, S., McTernan, P. G., Harte, A. L., McTernan, P., Bruno Schisano, Philip McTernan, Schisano, B., McGee, K. C., Kumar, S., Alison Harte, Tripathi, G., Kirsty McGee   +18 more
core   +1 more source

Contributions of Ccr4 and Gcn2 to the Translational Response of C. neoformans to Host-Relevant Stressors and Integrated Stress Response Induction

mBio, 2023
In response to the host environment, the human pathogen Cryptococcus neoformans must rapidly reprogram its translatome from one which promotes growth to one which is responsive to host stress.
Corey M. Knowles, David Goich, Amanda L. M. Bloom, Murat C. Kalem, John C. Panepinto   +4 more
doaj   +1 more source

Arabidopsis CCoAOMT1 Plays a Role in Drought Stress Response via ROS- and ABA-Dependent Manners

, 2021
Plants possess adaptive reprogramed modules to prolonged environmental stresses, including adjustment of metabolism and gene expression for physiological and morphological adaptation.
Jong Chan Hong, Dong Hyeon No, Min Chul Kim, Hyun Min Cho, Ye Jin Cha, Dongwon Baek, Hyun Jin Chun, Mi Suk Park, Su Hyeon Lee, Yong Bok Lee, Mi Sun Cheong, Byung Jun Jin, Dae-Jin Yun, Lack Hyeon Lim   +13 more
core   +1 more source

Higher use of techniques studied and performance in melee combat produce a higher psychophysiological stress response [PDF]

, 2018
We aimed to analyse the effectiveness of an operative training in soldiers' psychophysiological and melee combat performance. Nineteen soldiers performed a 50-hr training for 10 weeks. After training, they were divided into two groups: higher performance
Diaz Manzano, Montaña, Clemente Suárez, Vicente Javier, Fernández Lucas, Jesús, Vicente Javier Clemente‐Suárez, Fuentes García, Juan Pedro, Aznar Lain, Susana, Susana Aznar‐Lain, Montaña Diaz‐Manzano, Fuentes, Juan Pedro, Juan P. Fuentes, Fuentes, Juan P., Jesús Fernandez‐Lucas   +11 more
core   +1 more source

Arsenicals, the Integrated Stress Response, and Epstein–Barr Virus Lytic Gene Expression

Viruses, 2021
Following our observation that clofoctol led to Epstein–Barr virus (EBV) lytic gene expression upon activation of the integrated stress response (ISR), we decided to investigate the impact of As2O3 on viral lytic gene expression.
Jaeyeun Lee, Jennifer Stone, Prashant Desai, John G. Kosowicz, Jun O. Liu, Richard F. Ambinder   +5 more
doaj   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Functional Analysis of PbbZIP11 Transcription Factor in Response to Cold Stress in Arabidopsis and Pear

, 2023
Cold stress is a prominent abiotic factor that adversely affects the growth and yield of pears, consequently restricting the cultivation range and resulting in substantial economic losses for the pear industry.
Yuxin Zhang, Li Liu, Lun Liu, Wei Heng, Lin Wu, Zhenfeng Ye, Bing Jia, Xiaomei Tang   +7 more
core   +1 more source

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source

Inhibition of the integrated stress response reverses oxidative stress damage-induced postoperative cognitive dysfunction

Frontiers in Cellular Neuroscience, 2022
Postoperative cognitive dysfunction (POCD) is a common complication following anesthesia and surgery that might lead to a decline in learning and memory. Oxidative stress damage is one of the pathogenic mechanisms underlying POCD.
Linhao Jiang, Linhao Jiang, Linhao Jiang, Linhao Jiang, Rui Dong, Rui Dong, Rui Dong, Rui Dong, Minhui Xu, Minhui Xu, Minhui Xu, Yujia Liu, Yujia Liu, Yujia Liu, Yujia Liu, Jiyan Xu, Jiyan Xu, Jiyan Xu, Jiyan Xu, Zhengliang Ma, Tianjiao Xia, Tianjiao Xia, Tianjiao Xia, Xiaoping Gu   +23 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source