Results 31 to 40 of about 10,095,518 (284)
Integrative analysis of the salt stress response in cyanobacteria [PDF]
Biology Direct, 2021 Abstract Microorganisms evolved specific acclimation strategies to thrive in environments of high or fluctuating salinities. Here, salt acclimation in the model cyanobacterium Synechocystis sp.
Stephan Klähn +5 more
openaire +5 more sources
Innate Immune Recognition, Integrated Stress Response, Infection, and Tumorigenesis
Biology, 2023 Engagement of PRRs in recognition of PAMPs or DAMPs is one of the processes that initiates cellular stress. These sensors are involved in signaling pathways leading to induction of innate immune processes.
Klara Kubelkova +3 more
doaj +1 more source
Stress in healthy young women : psychophysiological stress response and sleep in the context of adverse childhood experiences and daily stress [PDF]
, 2014 The aim of the present dissertation is to contribute to the knowledge about different aspects of stress and their impact on healthy young women. The relationship between daily stress, presleep arousal, and sleep was investigated and additionally, the ...
Winzeler, Katja
core +1 more source
Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease
Antioxidants, 2021 Huntington’s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting ...
Bindu D. Paul
doaj +1 more source
From the integrated stress response to oxidative stress: A historical perspective. [PDF]
J Biol ChemOxidative stress has exerted fundamental evolutionary pressure since the emergence of aerobic life. Its impact on the physiology and function of all organisms is profound and consequential for cell survival. The integrated stress response (ISR) plays a critical role in counteracting oxidative stress via translational control of a subset of mRNAs. Here,
Amiri M +4 more
europepmc +3 more sources
The effect of a trapping procedure on the stress response of wild rainbow trout [PDF]
, 2002 Fish traps are a common research and management tool in which fish are subjected to procedures that elicit a stress response in other contexts. The effects of trapping on the stress response of sexually mature, wild rainbow trout Oncorhynchus mykiss were
Clements, Shaun P., Hicks, Brendan J.
core +1 more source
Integration of O-GlcNAc into Stress Response Pathways
Cells, 2022 The modification of nuclear, mitochondrial, and cytosolic proteins by O-linked βN-acetylglucosamine (O-GlcNAc) has emerged as a dynamic and essential post-translational modification of mammalian proteins. O-GlcNAc is cycled on and off over 5000 proteins in response to diverse stimuli impacting protein function and, in turn, epigenetics and ...
Kamau M. M. Fahie +2 more
openaire +3 more sources
Cell ReportsSummary: The majority of severe early-onset and juvenile cases of amyotrophic lateral sclerosis (ALS) are caused by mutations in the FUS gene, resulting in rapid disease progression.
Hafiza Alirzayeva +9 more
doaj +1 more source
EIF2α phosphorylation: a hallmark of both autophagy and immunogenic cell death
Molecular & Cellular Oncology, 2020 Different intrinsic and extrinsic stress pathways including endoplasmic reticulum (ER) stress converge on the phosphorylation of eukaryotic translation initiation factor 2A (EIF2A, best known as eIF2α), which characterizes the so-called “integrated ...
Juliette Humeau +3 more
doaj +1 more source
eIF2B-capturing viral protein NSs suppresses the integrated stress response
Nature Communications, 2021 Here the authors show that a viral protein interferes with the binding of phosphorylated eIF2 to eIF2B, thereby suppressing the host integrated stress response (ISR). This suppression of the ISR abrogates translational changes of the host and ameliorates
Kazuhiro Kashiwagi +10 more
doaj +1 more source