Results 81 to 90 of about 10,043,563 (299)

Stress, the cortisol awakening response and cognitive function [PDF]

, 2020
There is evidence that stress-induced disruption of the circadian rhythm of cortisol secretion, has negative consequences for brain health. The cortisol awakening response (CAR) is the most prominent and dynamic aspect of this rhythm.
Law, R., Robin Law, Angela Clow, Clow, A.   +3 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. [PDF]

, 2013
25-Hydroxycholesterol (25OHC) is an enzymatically derived oxidation product of cholesterol that modulates lipid metabolism and immunity. 25OHC is synthesized in response to interferons and exerts broad antiviral activity by as yet poorly characterized ...
Merrill, Alfred H, Maurya, Mano R, Fahy, Eoin, Russell, David W, Subramaniam, Shankar, Quehenberger, Oswald, Lam, Michael T, Saijo, Kaoru, Crotti, Andrea, Sullards, M Cameron, Spann, Nathanael J, Raetz, Christian RH, Cavener, Douglas R, Shibata, Norihito, Reichart, Donna, Romanoski, Casey E, Glass, Christopher K, Kaikkonen, Minna U, McDonald, Jeffrey G, Murphy, Robert C, Brown, H Alex, Spector, Deborah H, Morello, Christopher S, Fox, Jesse N, Dennis, Edward A, Carlin, Aaron F   +25 more
core   +1 more source

The integrated stress response system in cardiovascular disease

Drug Discovery Today, 2018
The integrated stress response system represents an ancillary, extremely conserved signalling pathway present in virtually all eukaryotic cells, which plays an important part in the pathophysiology of several disorders such as cancer and neurodegeneration. However, its role in the cardiovascular system remains largely elusive.
Diana, Santos-Ribeiro, Laurent, Godinas, Charles, Pilette, Frédéric, Perros   +3 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Ribosome Reinitiation Directs Gene-specific Translation and Regulates the Integrated Stress Response

, 2015
Young, S. K., Willy, J. A., Wu, C., Sachs, M. S., & Wek, R. C. (2015). Ribosome Reinitiation Directs Gene-specific Translation and Regulates the Integrated Stress Response. The Journal of Biological Chemistry, 290(47), 28257–28271. http://doi.org/10.1074/
Willy, Jeffrey A., Young, Sara K., Sachs, Matthew S., Wek, Ronald C., Wu, Cheng   +4 more
core   +1 more source

The role of sigma factor RpoH1 in the pH stress response of Sinorhizobium meliloti [PDF]

, 2010
de Lucena DK, Pühler A, Weidner S. The role of sigma factor RpoH1 in the pH stress response of Sinorhizobium meliloti. BMC Microbiology. 2010;10(1): 256.Background: Environmental pH stress constitutes a limiting factor for S.
Argandoña, Montserrat, Iglesias Guerra, Fernando, Jebbar Mohamed, Reina-Bueno Mercedes, Argandoña Montserrat, Mohamed Jebbar, Mercedes Reina-Bueno, Joaquín J Nieto, Reina Bueno, Mercedes, Argandoña Bertrán, Montserrat, Rodríguez-Moya, Javier, Vargas Macías, Carmen, Iglesias-Guerra Fernando, Jebbar, Mohamed, Nieto Joaquín J, Javier Rodríguez-Moya, Fernando Iglesias-Guerra, Vargas Carmen, de Lucena, Daniella Karine, Reina-Bueno, Mercedes, Rodríguez de Moya Vera, Javier, Pühler, Alfred ; https://orcid.org/, Iglesias-Guerra, Fernando, Weidner, Stefan, Nieto Gutiérrez, Joaquín José, Rodríguez-Moya Javier, Nieto, Joaquín J, Vargas, Carmen, Carmen Vargas, Montserrat Argandoña   +29 more
core   +1 more source

Integrated Endoplasmic Reticulum Stress Responses in Cancer [PDF]

Cancer Research, 2007
Abstract The endoplasmic reticulum (ER) has emerged as a major site of cellular homeostasis regulation, particularly in the unfolded protein response, which is being found to play a major role in cancer and many other diseases. Here, we address ER-mediated signaling and regulations in the context of environmental challenges in cancer ...
Michel, Moenner, Olivier, Pluquet, Marion, Bouchecareilh, Eric, Chevet   +3 more
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Exploring the Relationship between Childhood Interpersonal Violence, Cortisol Stress Response, and Stress Eating [PDF]

, 2013
Histories of childhood interpersonal violence have been linked to overweight and obesity in adulthood. Despite the fact that victimization experiences are likely to co-occur within individuals, few studies have examined poly-victimization in the context ...
Midei, Aimee J
core