Results 21 to 30 of about 154,422 (243)
Clinical proteomics for precision medicine: the bladder cancer case [PDF]
, 2017 Precision medicine can improve patient management by guiding therapeutic decision based on molecular characteristics. The concept has been extensively addressed through the application of –omics based approaches.
Frantzi, Maria +4 more
core +1 more source
Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap
iScience, 2020 Summary: Integration of transforming growth factor β (TGF-β) signals with those of other pathways allows for precise temporal and spatial control of gene expression patterns that drive development and homeostasis. The Hippo pathway nuclear effectors, Taz/
Bita Labibi +3 more
doaj +1 more source
, 2018 New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome, phenotype, and ...
Goldenberg, Anna +5 more
core +1 more source
The Evolution of Student Engagement: Writing Improves Teaching in Introductory Biology [PDF]
, 2021 In response to calls for pedagogical reforms in undergraduate biology courses to decrease student attrition rates and increase active learning, this article describes one faculty member’s conversion from traditional teaching methods to more engaging ...
Camfield, Eileen, Land, Kirkwood
core +1 more source
Effect of macromolecular crowding on the kinetics of glycolytic enzymes and the behaviour of glycolysis in yeast [PDF]
, 2018 Water is involved in all aspects of biological activity, both as a solvent and as a reactant. It is hypothesized that intracellular water is in a highly structured state due to the high concentrations of macromolecules in the cell and that this may ...
Bagatolli, Luis Alberto +2 more
core +2 more sources
Integrative modeling of the cell
Acta Biochimica et Biophysica Sinica, 2022 A whole-cell model represents certain aspects of the cell structure and/or function. Due to the high complexity of the cell, an integrative modeling approach is often taken to utilize all available information including experimental data, prior knowledge
Zhong Xianni, Zhao Jihui, Sun Liping
doaj +1 more source
Minimum Information About a Simulation Experiment (MIASE) [PDF]
, 2011 Reproducibility of experiments is a basic requirement for science. Minimum Information (MI) guidelines have proved a helpful means of enabling reuse of existing work in modern biology. The Minimum Information Required in the Annotation of Models (MIRIAM)
Hucka, Michael, Waltemath, Dagmar
core +3 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Antigen self-anchoring onto bacteriophage T5 capsid-like particles for vaccine design
npj VaccinesThe promises of vaccines based on virus-like particles stimulate demand for universal non-infectious virus-like platforms that can be efficiently grafted with large antigens.
Emeline Vernhes +14 more
doaj +1 more source
Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions
iScienceSummary: The mechanisms underlying the pathophysiology of endometriosis, characterized by the presence of endometrium-like tissue outside the uterus, remain poorly understood.
Gregory W. Burns +6 more
doaj +1 more source