Results 31 to 40 of about 145,713 (206)
Multi-omics integration reveals molecular networks and regulators of psoriasis. [PDF]
, 2019 BackgroundPsoriasis is a complex multi-factorial disease, involving both genetic susceptibilities and environmental triggers. Genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS) have been carried out to identify genetic ...
Arneson, Douglas +5 more
core +3 more sources
bioRxiv, 2020 To meet the growing demands from scientists to effectively extract deep insights from single cell RNA sequencing, spatial transcriptomics, and emerging multiome datasets, we developed cellxgene VIP (Visualization In Plugin), a frontend interactive ...
Kejie Li +8 more
semanticscholar +1 more source
Systems biology in animal sciences [PDF]
, 2011 Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Bannink, A. +4 more
core +3 more sources
Implications of Big Data for cell biology
Molecular Biology of the Cell, 2015 “Big Data” has surpassed “systems biology” and “omics” as the hottest buzzword in the biological sciences, but is there any substance behind the hype? Certainly, we have learned about various aspects of cell and molecular biology from the many individual
K. Dolinski, O. Troyanskaya
semanticscholar +1 more source
Integrative characterization of the near‐minimal bacterium Mesoplasma florum
Molecular Systems Biology, 2020 The near‐minimal bacterium Mesoplasma florum is an interesting model for synthetic genomics and systems biology due to its small genome (~ 800 kb), fast growth rate, and lack of pathogenic potential.
Dominick Matteau +9 more
semanticscholar +1 more source
Flexibility in the Patterning and Control of Axial Locomotor Networks in Lamprey [PDF]
, 2011 In lower vertebrates, locomotor burst generators for axial muscles generally produce unitary bursts that alternate between the two sides of the body. In lamprey, a lower vertebrate, locomotor activity in the axial ventral roots of the isolated spinal ...
Buchanan, James T.
core +2 more sources
iScience, 2020 Summary: Cell-cycle quiescence is a common feature of early germline development in many animal species. In Drosophila germline progenitors (pole cells), both G2/M and G1/S transitions are blocked.
Shumpei Morita +3 more
doaj +1 more source
Ontology-assisted database integration to support natural language processing and biomedical data-mining [PDF]
, 2004 Successful biomedical data mining and information extraction require a complete picture of biological phenomena such as genes, biological processes, and diseases; as these exist on different levels of granularity.
Ceusters, Werner +4 more
core +1 more source
BacillOndex: An Integrated Data Resource for Systems and Synthetic Biology [PDF]
, 2013 BacillOndex is an extension of the Ondex data integration system, providing a semantically annotated, integrated knowledge base for the model Gram-positive bacterium Bacillus subtilis. This application allows a user to mine a variety of B.
Allenby, Nick +7 more
core +2 more sources
How to address cellular heterogeneity by distribution biology [PDF]
, 2017 Cellular heterogeneity is an immanent property of biological systems that covers very different aspects of life ranging from genetic diversity to cell-to-cell variability driven by stochastic molecular interactions, and noise induced cell differentiation.
N. Komin, A. Skupin
semanticscholar +1 more source