Results 21 to 30 of about 167,996,906 (262)

Evolutionary cell biology: Functional insight from “Endless forms most beautiful” [PDF]

, 2015
In animal and fungal model organisms, the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level.
Richardson, Elizabeth, Dacks, Joel B., Tsaousis, Anastasios D., Dorrell, Richard G., Zerr, Kelly   +4 more
core   +1 more source

Spatial regulation of MCAK promotes cell polarization and focal adhesion turnover to drive robust cell migration

, 2021
The asymmetric distribution of microtubule (MT) dynamics in migrating cells is important for cell polarization, yet the underlying regulatory mechanisms remain underexplored.
Hazelbaker, Mark, Moe, Christina, Walczak, Claire E., Zong, Hailing, Ems-McClung, Stephanie C., Hu, Ke   +5 more
core   +1 more source

Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]

, 2011
The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
Haastert, Peter J.M. van,, Peter J M van Haastert, van Haastert, Peter J. M., van Haastert, Peter J.M., Matthew P. Neilson, Douwe M Veltman, Webb, Steven D., Insall, Robert H., Webb, Steven D.,, Neilson, Matthew P.,, Neilson, Matthew P., Matthew P Neilson, Douwe M. Veltman, Peter J. M. van Haastert, Insall, Robert H.,, Steven D Webb, Webb, Steven, Robert H Insall, John A. Mackenzie, Mackenzie, John A.,, John A Mackenzie, Veltman, Douwe M.,, Mackenzie, John A., Veltmahn, Douwe M., Veltman, Douwe M., Steven D. Webb, Robert H. Insall   +26 more
core   +5 more sources

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

, 2014
Peer ...
Findlay, Amy S., Ouyang, Zhufeng, Zakrewska, Ewa, Kuan, Soh-Leh, Durward, Elaine, Nakamoto, Masaru, Findlay, Amy, Zakrzewska, Ewa, Nakamoto, Chizu, Kuan, Soh Leh, Endo, Takuma   +10 more
core   +1 more source

Implications of Big Data for cell biology

, 2015
“Big Data” has surpassed “systems biology” and “omics” as the hottest buzzword in the biological sciences, but is there any substance behind the hype? Certainly, we have learned about various aspects of cell and molecular biology from the many individual
Dolinski, Kara, Troyanskaya, Olga
core   +1 more source

Quantitative proteomics and RNA-sequencing of mouse liver endothelial cells identify novel regulators of BMP6 by iron

iScience, 2023
Summary: Hepcidin is the master hormone governing systemic iron homeostasis. Iron regulates hepcidin by activating bone morphogenetic protein (BMP)6 expression in liver endothelial cells (LECs), but the mechanisms are incompletely understood.
Allison L. Fisher, Chia-Yu Wang, Yang Xu, Sydney Phillips, Joao A. Paulo, Beata Małachowska, Xia Xiao, Wojciech Fendler, Joseph D. Mancias, Jodie L. Babitt   +9 more
doaj   +1 more source

The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation [PDF]

, 2011
Peer ...
Raghuraman, M. K., Gina M. Alvino, Shin-ichiro Hiraga, Lian, Huiyong, Donaldson, Anne Dunlop, Brewer, Bonita J., Alvino, Gina M., Heather J. McCune, Collingwood, David, David Collingwood, Hui-Yong Lian, Sridhar, Akila, Anne D. Donaldson, Robertson, Euan Douglas, Hiraga, Shinichiro, McCune, H. J., Akila Sridhar, E. Douglas Robertson, Bonita J. Brewer, M. K. Raghuraman   +19 more
core   +1 more source

Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap

iScience, 2020
Summary: Integration of transforming growth factor β (TGF-β) signals with those of other pathways allows for precise temporal and spatial control of gene expression patterns that drive development and homeostasis. The Hippo pathway nuclear effectors, Taz/
Bita Labibi, Mikhail Bashkurov, Jeffrey L. Wrana, Liliana Attisano   +3 more
doaj   +1 more source

Building a path in cell biology

, 2012
Setting up a new lab is an exciting but challenging prospect. We discuss our experiences in finding a path to tackle some of the key current questions in cell biology and the hurdles that we have encountered along the ...
Cheeseman, Iain M, Voeltz, Gia
core   +1 more source

TFIIIC Localizes Budding Yeast ETC Sites to the Nuclear Periphery [PDF]

, 2012
Peer ...
Hiraga, Shin Ichiro, Hiraga, Shinichiro, Donze, David, Donaldson, Anne Dunlop, Donaldson, Anne D., Botsios, Sotirios   +5 more
core   +1 more source