Results 11 to 20 of about 167,996,906 (262)

Glycosylation network mapping and site-specific glycan maturation in vivo

iScience, 2022
Summary: Glycoprotein processing along a complex highly compartmentalized pathway is a hallmark of eukaryotic cells. We followed the kinetics of intracellular, site-specific glycan processing of a model protein with five distinct N-glycosylation sites ...
Marie-Estelle Losfeld, Ernesto Scibona, Chia-wei Lin, Markus Aebi   +3 more
doaj   +1 more source

Population dynamics of EMT elucidates the timing and distribution of phenotypic intra-tumoral heterogeneity

iScience, 2023
Summary: The Epithelial-to-Mesenchymal Transition (EMT) is a hallmark of cancer metastasis and morbidity. EMT is a non-binary process, and cells can be stably arrested en route to EMT in an intermediate hybrid state associated with enhanced tumor ...
Annice Najafi, Mohit K. Jolly, Jason T. George   +2 more
doaj   +1 more source

Constraint-based modeling of yeast mitochondria reveals the dynamics of protein import and iron-sulfur cluster biogenesis

iScience, 2021
Summary: Mitochondria are a hallmark of eukaryal cells and play an important role in cellular metabolism. There is a vast amount of knowledge available on mitochondrial metabolism and essential mitochondrial functions, such as protein import and iron ...
Carl Malina, Francesca Di Bartolomeo, Eduard J. Kerkhoven, Jens Nielsen   +3 more
doaj   +1 more source

A Conserved Cell Growth Cycle Can Account for the Environmental Stress Responses of Divergent Eukaryotes [PDF]

, 2012
The respiratory metabolic cycle in budding yeast (Saccharomyces cerevisiae) consists of two phases most simply defined phenomenologically: low oxygen consumption (LOC) and high oxygen consumption (HOC).
Airoldi, Edoardo|, Airoldi, E.M., Airoldi, EM, Airoldi, Edoardo M, Botstein, D., van Oudenaarden, Alexander, Airoldi, Edoardo, Van Oudenaarden, A, Botstein, David, Slavov, Nikolai G, Botstein, D, Slavov, N., Airoldi, Edoardo M., Slavov, N, van Oudenaarden, A., Slavov, Nikolai   +15 more
core   +1 more source

Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology [PDF]

, 2009
The use of computational modeling and simulation has increased in many biological fields, but despite their potential these techniques are only marginally applied in nutritional sciences.
Ommen, Ben van, De Roos Baukje, Ommen, Ben van,, van Ommen Ben, van Ommen, Ben, Graaf, A.A. de, Martin Adiels, Adiels, Martin,, Rullmann, Johan A.C., Roos, Baukje de, Kevin D. Hall, de Graaf Albert A., Freidig, Andreas P.,, Hall, Kevin D.,, Neema Jamshidi, Andreas P. Freidig, Adiels, M., Hall, Kevin D, Hall Kevin D., Baukje De Roos, Johan A C Rullmann, Rullmann, J.A.C., Ben van Ommen, Graaf, Albert A. de, Rullmann Johan A.C., Freidig, Andreas P, Andreas P Freidig, Jamshidi Neema, Jamsheedi, Neema, Heinemann, M., Heinemann Matthias, Roos, B. de, Johan A.C. Rullmann, Adiels Martin, De Roos, Baukje, Ommen, B. van, Albert A de Graaf, Jamshidi, Neema,, de Graaf, Albert A, Adiels, Martin, Hall, K.D., Freidig, Andreas P., Heinemann, Matthias,, Hall, Kevin D., Roos, Baukje de,, Rullmann, Johan A C, Heinemann, Matthias; id_orcid, Albert A. de Graaf, Freidig Andreas P., Rullmann, Johan AC, Graaf, Albert A. de,, Freidig, A.P., Heinemann, Matthias, Matthias Heinemann, Rullmann, Johan A.C.,, Jamshidi, Neema, Jamshidi, N., Kevin D Hall   +57 more
core   +3 more sources

UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence [PDF]

, 2008
Publications prior to 2012 under name Thompson, D.S.Peer ...
Monteagudo, Carlos, Banerjee, Mohua, López-Ribot, José L, Kadosh, David, Pierce, Christopher, Thompson, Delma S, Lazzell, Anna, Carlisle, Patricia L   +7 more
core   +1 more source

The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway [PDF]

, 2009
© 2009 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,.
Jacquier, N, Höfken, T, Lin, Meng, Jacquier, Nicolas, Schneiter, R, Unden, H, Just, Ursula, Just, U, Unden, Heike, Höfken, Thomas, Schneiter, Roger   +10 more
core   +1 more source

A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes [PDF]

, 2013
peer reviewedWe present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a
Carroll, Kathleen M, Paton, Norman W, Mendes, Pedro, McCarthy, John E G, Carroll, K.M., Weichart, D., Broomhead, David S., Murabito, Ettore, Khan, Farid, Messiha, Hanan L.,, Dunn, Warwick B., Oliver, Stephen G,, Swainston, N., Broomhead, D. S., Dada, Joseph O., Oliver, Stephen G., Westerhoff, H.V.; id_orcid, Kell, Douglas B.,, Kell, D.B., Gaskell, Simon J, Winder, Catherine L., Malys, Naglis, Dada, J.O., Westerhoff, Hans V.,, Pir, P., Paton, N.W., Pendes, Pedro, Pir, Pınar,, Murabito, Ettore,, Messiha, H.L., Paton, Norman W., Westerhoff, Hans V., Gaskell, Simon J., Dunn, Warwick B.,, Simeonidis, E., Kell, Douglas B., Simeonidis, Evangelos,, Khan, Farid,, Jameson, Daniel; id_orcid, Gaskell, S.J., Jameson, Daniel, Dada, Joseph O, Carroll, Kathleen M.,, Spasić, I., Kell, Douglas B, Smallbone, K., Winder, Catherine L, Mendes, P., McCarthy, John E. G., Hayes, Neil W., Paton, Norman; id_orcid, Spasic, Irena, Weichart, Dieter, Pir, Pınar, Gaskell, S. J., Carroll, Kathleen M., Dunn, W.B., Jameson, Daniel,, Jameson, D., Gaskell, Simon J.,, Malys, N., Paton, Norman W.,, Malys, Naglis,, SIMEONIDIS, Vangelis, Smallbone, Kieran,, Simeonidis, Evangelos, Wishart, J., Messiha, Hanan L, Wishart, Jill,, Westerhoff, Hans V, McCarthy, John E G,, Murabito, E., Khan, F., Oliver, Stephen G, Wishart, Jill, Broomhead, David S, Messiha, Hanan L., Dunn, Warwick B, Winder, C.L., Jameson, D,, Dada, Joseph O.,, Swainston, Neil,, Weichart, Dieter,, Oliver, S. G., Hayes, N.W., Pir, Pinar, Spasić, Irena,, Broomhead, D.S., Mendes, Pedro,, Broomhead, David S.,, McCarthy, John E.G., Hayes, Neil W, Hayes, Neil W.,, Oliver, S.G., Swainston, Neil, Smallbone, Kieran, McCarthy, J.E.G., Winder, Catherine L.,, Westerhoff, H.V., Carroll, Kathleen M; id_orcid   +99 more
core   +2 more sources

04281 Abstracts Collection – Integrative Bioinformatics - Aspects of the Virtual Cell [PDF]

, 2006
From 04.07.04 to 09.07.04, the Dagstuhl Seminar 04281 ``Integrative Bioinformatics - Aspects of the Virtual Cell'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl.
Hofestädt, Ralf, Collado-Vides, Julio, Sensen, Christoph W.   +2 more
core   +1 more source

A Richer and More Diverse Future for Cell Biology [PDF]

, 2010
Our vision: within the next few decades the composition of the faculty of cell biology, and of all biological science departments, will reflect the diverse composition of the graduate students in those departments.
Virginia Valian, Phoebe Leboy, Valian, Virginia, Masur, Sandra, Hopkins, Nancy, Sandra L. Schmid, Nancy Hopkins, Ursula Goodenough, Molly Carnes, Goodenough, Ursula, Leboy, Phoebe, Sandra Masur, Carnes, Molly, Hopkins, Nancy H., Schmid, Sandra L.   +14 more
core   +1 more source