Results 261 to 270 of about 416,319 (333)

Integrin‐linked kinase regulates endothelial cell nitric oxide synthase expression in hepatic sinusoidal endothelial cells

, 2014
Mahnoush S. Shafiei, Songling Lui, Don C. Rockey   +2 more
openalex   +2 more sources

An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring

Advanced Science, EarlyView.
Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar, Marc A. Fernandez‐Yague, Adrien Bessaguet, Hosoowi Lee, Nicolas Giuseppone, Andrés J. García, Aránzazu del Campo   +6 more
wiley   +1 more source

Sulfatide Acts as a Regulatory Molecule Controlling β1 Integrin-STAT5 Signaling and BOLA2-Dependent Apoptotic Pathway in Breast Cancer Cells. [PDF]

Int J Mol Sci
Suchanski J, Woldanska W, Sciana A, Suchanska B, Moniakowski L.   +4 more
europepmc   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Bone sialoprotein: a multifunctional regulator of bone remodelling and tumour progression. [PDF]

Bone Res
Kottmann V, Drees P, Gercek E, Ritz U.
europepmc   +1 more source

Beta1-integrin and TRPV4 are involved in osteoblast adhesion to different titanium surface topographies

, 2019
Federico Mussano, Tullio Genova, Marco Laurenti, Deborah Gaglioti, Giorgia Scarpellino, Paola Rivolo, Maria Giulia Faga, Alessandra Fiorio, Luca Munaron, Pietro Mandracci, Stefano Carossa   +10 more
openalex   +2 more sources

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Ly6/uPAR Protein from <i>Asterias rubens</i> Starfish Stimulates Migration and Invasion of Human Epithelial and Immune Cells. [PDF]

Mar Drugs
Lyukmanova EN, Gornostaeva TY, Shabelnikov SV, Shenkarev ZO, Kirpichnikov MP, Paramonov AS, Bychkov ML.   +6 more
europepmc   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Anoikis: To Die or Not to Die? [PDF]

Int J Mol Sci
Koltai T, Fliegel L.
europepmc   +1 more source