Results 21 to 30 of about 86,429 (265)

Human Parechovirus 1 Infection Occurs via αVβ1 Integrin. [PDF]

PLoS ONE, 2016
Human parechovirus 1 (HPeV-1) (family Picornaviridae) is a global cause of pediatric respiratory and CNS infections for which there is no treatment.
Pirjo Merilahti, Sisko Tauriainen, Petri Susi   +2 more
doaj   +1 more source

WITHDRAWN: Galectin-3 carbohydrate recognition domain induces microvascular endothelial cell migration by activating β1 Integrin

Oncotarget, 2018
// Zhongyu Zhang 1 , Yuan Guan 1 , Xiyao Yu 1 , Hairong Cheng 1 , Yifa Zhou 1 and Guihua Tai 1 1 School of Life Sciences, Northeast Normal University, Changchun, PR China Correspondence to: Guihua Tai, email: taigh477@nenu.edu.cn Keywords : galectin-3; CRD; migration; HMEC-1; β1 integrin Received: August 18, 2017     Accepted ...
Zhongyu Zhang, Zhongyu Zhang, Yuan Guan, Yuan Guan, Xiyao Yu, Xiyao Yu, Hairong Cheng, Hairong Cheng, Yifa Zhou, Yifa Zhou, Guihua Tai, Guihua Tai   +11 more
openaire   +1 more source

Epidermal growth factor-mediated Rab25 pathway regulates integrin β1 trafficking in colon cancer

Cancer Cell International, 2018
Background Integrins play a critical role in carcinogenesis. Integrin β1 localization is regulated by the guanosine-5′-triphosphate hydrolase Rab25 and integrin β1 levels are elevated in the serum of colon cancer patients; thus, the present study ...
Kyung Sook Hong, Eun-Young Jeon, Soon Sup Chung, Kwang Ho Kim, Ryung-Ah Lee   +4 more
doaj   +1 more source

Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis [PDF]

, 2016
β1-Integrins are essential for angiogenesis. The mechanisms regulating integrin function in endothelial cells (EC) and their contribution to angiogenesis remain elusive.
Bennewitz, Katrin, Carmona, Guillaume, Chavakis, Emmanouil, Dimmeler, Stefanie, Gutkind, J. Silvio, Kroll, Jens, Li, Xuri, Manavski, Yosif, Sakurai, Atsuko, Tang, Zhongshu, Zeiher, Andreas M., Zhang, Fan   +11 more
core   +1 more source

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and b1-integrin activation [PDF]

, 2018
Lymphatic invasion and lymph node metastasis correlate with poor clinical outcome in melanoma. However, the mechanisms of lymphatic dissemination in distant metastasis remain incompletely understood.
Alve, S, Balistreri, G, Gramolelli, S, Hautaniemi, S, Icay, K, Ivaska, J, Lehti, K, Niiranen, O, Ojala, PM, Paatero, I, Pekkonen, P, Perälä, N, Repo, P, Saharinen, P, Taiwo, A, Tatti-Bugaeva, O, Tuohinto, K, Zinovkina, N   +17 more
core   +1 more source

Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells [PDF]

, 2018
Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression.
Acconcia, Acconcia, Acerbi, Adlanmerini, Alfredo Cáceres, Ambrose, Andrés M. Toscani, Arjonen, Arnal, Axelrod, Axelrod, Bacia, Bae, Barabas, Bates, Bermudez-Hernandez, Bonifacino, Bradford, Cancer Genome Atlas Network, Caswell, Cerami, Chaumet, Chung, Ciriello, Ciriello, Correia, Cosker, Cosker, Couse, Cox, Dante R. Chialvo, De Franceschi, Debnath, Degasperi, Delcroix, Dozynkiewicz, Dunn, Eirew, Federico Coluccio Leskow, Fernando D. Stefani, Gao, Gao, Ghajar, Gillespie, Gould, Graham, Grant, Han, Han, Hartley, He, Heery, Helleman, Hernández, Hines, Honerkamp-Smith, Ianina L. Violi, Jeselsohn, Johnson, Jonathon N. Lakins, Kate Thi, Kisler, La Rosa, Letoha, Levin, Li, Long, Lu, Lu, Luciano A. Masullo, Luzio, Mak, Marina Simian, Marino, Matthew G. Rubashkin, Mayor, Mayor, Małecki, McDonough, Mina J. Bissell, Moreno-Layseca, Nam, Nardone, Nicovich, Ovesný, Pedram, Pereira, Pietras, Pontiggia, Razandi, Reid, Rocío G. Sampayo, Rust, Savkur, Schindelin, Schlegel, Skliris, Solowska, Su, Sung, Takahashi, Tiwari, Totta, Totta, Upla, Valerie M. Weaver, van de Linde, Vanlandingham, Wang, Waxmonsky, William C. Hines, Yao   +111 more
core   +2 more sources

The linkage between β1 integrin and the actin cytoskeleton is differentially regulated by tyrosine and serine/threonine phosphorylation of β1 integrin in normal and cancerous human breast cells

BMC Cell Biology, 2001
Background Structural requirements for the β1 integrin functions in cell adhesion, spreading and signaling have been well documented mainly for fibroblasts.
Takahashi Kazuhide
doaj   +1 more source

Integrin β1 is a key determinant of the expression of angiotensin-converting enzyme 2 (ACE2) in the kidney epithelial cells.

European Journal of Cell Biology, 2023
The expression of the angiotensin-converting enzyme 2 (ACE2) is altered in multiple chronic kidney diseases like hypertension and renal fibrosis, where the signaling from the basal membrane proteins is critical for the development and progression of the ...
Md Saimon Mia, Delowar Hossain, Emerson Woodbury, Sean Kelleher, Riya.J. Palamuttam, Reena Rao, Preston Steen, Yagna PR Jarajapu, Sijo Mathew   +8 more
doaj   +1 more source

Integrin β1 regulates the invasion and radioresistance of laryngeal cancer cells by targeting CD147

Cancer Cell International, 2018
Background Increased expression of integrin β1 has been reported to correlate with progression and therapy resistance in many types of cancers. The aim of this study was to investigate the effects of integrin β1 on the invasion and radioresistance of ...
Li Li, Xiaoxia Dong, Feng Peng, Li Shen
doaj   +1 more source

Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface. [PDF]

PLoS ONE, 2013
Proliferative vitreoretinopathy (PVR) is a blinding disease frequently occurring after retinal detachment surgery. Adhesion, migration and matrix remodeling of dedifferentiated retinal pigment epithelial (RPE) cells characterize the onset of the disease.
Claudia S Priglinger, Christoph M Szober, Siegfried G Priglinger, Juliane Merl, Kerstin N Euler, Marcus Kernt, Gabor Gondi, Jennifer Behler, Arie Geerlof, Anselm Kampik, Marius Ueffing, Stefanie M Hauck   +11 more
doaj   +1 more source