Results 31 to 40 of about 86,429 (265)

Regulation of opticin on bioactivity of retinal vascular endothelial cells cultured in collagen [PDF]

International Journal of Ophthalmology, 2020
AIM: To investigate the effects of collagen and opticin on the bioactivity of human retinal vascular endothelial cells (hRVECs), and explore its regulations by integrins and RhoA/ROCK1 signal pathway.
Yue Xing, Xue-Ke Li, Si-Duo Lu, Jin Ma
doaj   +1 more source

β1 Integrins Show Specific Association with CD98 Protein in Low Density Membranes [PDF]

, 2012
Background: The CD98 (4F2, FRP-1) is a widely expressed cell surface protein heterodimer composed of a glycosylated heavy chain and a non-glycosylated light chain.
Berditchevski, Fedor, Hemler, Martin Edward, Kolesnikova, Tatiana V, Mannion, Brian A   +3 more
core   +1 more source

Regulation of pancreatic cancer aggressiveness by stromal stiffening [PDF]

, 2016
No abstract ...
A Neesse, AD Rhim, BC Özdemir, H Laklai, I Barbieri, JJ Lee, JK Mouw, JM Bailey, Michael F Olson, Nicola Rath, P Bailey, SR Hingorani, SR Hingorani, V Sanz-Moreno   +13 more
core   +1 more source

Integrin β1 Gene Therapy Enhances in Vitro Creation of Tissue-Engineered Cartilage Under Periodic Mechanical Stress

Cellular Physiology and Biochemistry, 2015
Background/Aims: Periodic mechanical stress activates integrin β1-initiated signal pathways to promote chondrocyte proliferation and matrix synthesis. Integrin β1 overexpression has been demonstrated to play important roles in improving the activities ...
Wenwei Liang, Chunhui Zhu, Feng Liu, Weiding Cui, Qing Wang, Zhefeng Chen, Qijia Zhou, Shun Xu, Chenjun Zhai, Weimin Fan   +9 more
doaj   +1 more source

Myelination: all about Rac n roll. [PDF]

, 2007
During the development of the peripheral nervous system, Schwann cells select individual axons from a nerve bundle and establish a one-to-one relationship through a process termed radial sorting. Recent findings identify the Rho family GTPase Rac1 as the
Chan, Jonah
core   +2 more sources

α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. [PDF]

, 2017
Tumors are fibrotic and characterized by abundant, remodeled, and cross-linked collagen that stiffens the extracellular matrix stroma. The stiffened collagenous stroma fosters malignant transformation of the tissue by increasing tumor cell tension to ...
Cassereau, L, García, AJ, Gooch, KJ, Hannachi, E-I, Miroshnikova, YA, Mouw, JK, Ou, G, Pickup, M, Rozenberg, GI, Sarang-Sieminski, AL, Templeman, KL, Weaver, VM   +11 more
core   +2 more sources

RGD-Binding Integrins in Head and Neck Cancers [PDF]

, 2017
YesAlterations in integrin expression and function promote tumour growth, invasion, metastasis and neoangiogenesis. Head and neck cancers are highly vascular tumours with a tendency to metastasise.
Brennan, Goswami, Hanadi Ahmedah, Hayashido, Helen Sheldrake, Huang, Jones, Jung, Kumar, Laurence Patterson, Lee, Li, Liu, Liu, Ni, Ramos, Steven Shnyder, Tambet, Trikha, Wichmann   +19 more
core   +1 more source

Analysis of the expression and prognostic value of MT1-MMP, β1-integrin and YAP1 in glioma

Open Medicine, 2022
Increased expression of membrane type 1-matrix metalloproteinase (MT1-MMP/MMP14) is associated with the development of many cancers. MT1-MMP may promote the entry of yes-associated protein1 (YAP1) into the nucleus by regulating the regulation of β1 ...
Zhai Yangyang, Sang Wei, Su Liping, Shen Yusheng, Hu Yanran, Zhang Wei   +5 more
doaj   +1 more source

Elucidation of the Roles of Tumor Integrin  1 in the Extravasation Stage of the Metastasis Cascade [PDF]

, 2018
Tumor integrin β1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles in extravasation have not yet been clearly elucidated.
Chen, Michelle B., Hynes, Richard O., Kamm, Roger Dale, Lamar, John, Li, Ran   +4 more
core   +1 more source

Atomic Force Microscopy-Based Nanoscopy of Chondrogenically Differentiating Human Adipose-Derived Stem Cells: Nanostructure and Integrin β1 Expression

Nanoscale Research Letters, 2018
Integrin β1 is known to be involved in differentiation, migration, proliferation, wound repair, tissue development, and organogenesis. In order to analyze the binding probability between integrin β1 ligand and cluster of differentiation 29 (CD29 ...
Jie Yang, Ming-Tang He, Xun Huang, Qiu-Shi Wang, Jiang Pi, Hua-Jun Wang, Ali Hasan Rahhal, Si-Min Luo, Zhen-Gang Zha   +8 more
doaj   +1 more source