Results 61 to 70 of about 234,137 (355)
Tensin links energy metabolism to extracellular matrix assembly. [PDF]
, 2017 The regulation of integrin function is key to fundamental cellular processes, including cell migration and extracellular matrix (ECM) assembly. In this issue, Georgiadou et al. (2017. J. Cell Biol.
Calderwood +15 more
core +3 more sources
Cell Death and Disease, 2019 Alzheimer´s disease (AD) is characterized by a progressive cognitive decline that correlates with the levels of amyloid β-peptide (Aβ) oligomers. Strong evidences connect changes of oligodendrocyte function with the onset of neurodegeneration in AD ...
Tania Quintela-López +8 more
semanticscholar +1 more source
β1 Integrins Show Specific Association with CD98 Protein in Low Density Membranes [PDF]
, 2012 Background: The CD98 (4F2, FRP-1) is a widely expressed cell surface protein heterodimer composed of a glycosylated heavy chain and a non-glycosylated light chain.
Berditchevski, Fedor +3 more
core +1 more source
Glycogen synthase kinase-3β plays a pro-apoptotic role in β-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes: Role of β1 integrins [PDF]
Journal of Molecular and Cellular Cardiology, 2007 Beta-adrenergic receptor (beta-AR) stimulation induces apoptosis in adult rat ventricular myocytes (ARVM). beta1 integrin signaling plays a protective role in beta-AR-stimulated apoptosis. Glycogen synthase kinase-3beta (GSK-3beta), a multifunctional serine/threonine kinase, negatively regulates cardiac hypertrophy.
Menon, Bindu +4 more
openaire +4 more sources
Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation [PDF]
, 2010 Objective: Increased levels of circulating tissue factor (TF) in the form of microparticles increase the risk of thrombosis. However, any direct influence of microparticle-associated TF on vascular endothelial cell proliferation is not known.
Collier, Mary E. W., Ettelaie, Camille
core +1 more source
Nanoscale Research Letters, 2018 Integrin β1 is known to be involved in differentiation, migration, proliferation, wound repair, tissue development, and organogenesis. In order to analyze the binding probability between integrin β1 ligand and cluster of differentiation 29 (CD29 ...
Jie Yang +8 more
doaj +1 more source
Expression of GIRK (Kir3.1/Kir3.4) channels in mouse fibroblast cells with and without β1 integrins
FEBS Letters, 2000 G protein‐activated K+ channel (GIRK) subunits possess a conserved extracellular integrin‐binding motif (RGD) and bind directly to β1 integrins. We expressed GIRK1/GIRK4 channels labeled with green fluorescent protein in fibroblast cell lines expressing or lacking β1 integrins.
Ivanina, Tatiana +6 more
openaire +4 more sources
Myelination: all about Rac n roll. [PDF]
, 2007 During the development of the peripheral nervous system, Schwann cells select individual axons from a nerve bundle and establish a one-to-one relationship through a process termed radial sorting. Recent findings identify the Rho family GTPase Rac1 as the
Chan, Jonah
core +2 more sources
, 2017 Additional file 1. Additional information. Details of experimental procedure and Additional figures S1, S2 and S3.
Babel, Laura +4 more
openaire +1 more source
Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins. [PDF]
, 2015 GIV/Girdin is a multimodular signal transducer and a bona fide metastasis-related protein. As a guanidine exchange factor (GEF), GIV modulates signals initiated by growth factors (chemical signals) by activating the G protein Gαi.
Ghosh, Pradipta +6 more
core +1 more source