Results 101 to 110 of about 118,295 (302)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Genistein induces a protective immunomodulatory effect in a mouse model of cervical cancer [PDF]

, 2012
Background: Genistein (GEN), a naturally occurring flavonoid present in soy bean, has attracted scientific interest for its possible benefits in cancer. Objective: The potential immunomodulatory effects of genistein on the immune system and against TC-1 ...
Alizadeh, A., Ghaemi, A., Gorji, A., Moradi, A., Razeghi, S., Soleimanjahi, H., Tabaraei, A., Vakili, M.A.   +7 more
core   +1 more source

Interferon-gamma release assays for the diagnosis of tuberculosis and tuberculosis infection in HIV-infected adults: a systematic review and meta-analysis. [PDF]

, 2014
Background: Despite the widespread use of interferon-gamma release assays (IGRAs), their role in diagnosing tuberculosis and targeting preventive therapy in HIV-infected patients remains unclear.
Muñoz López, Laura, Rigau, David, Santín Cerezales, Miguel   +2 more
core   +2 more sources

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Diagnosis of tuberculosis infection using interferon-γ-based assays [PDF]

, 2014
Interferon-γ-based assays, collectively known as IFN-γ release assays (IGRAs), have emerged as a reliable alternative to the old tuberculin skin test (TST) for the immunodiagnosis of tuberculosis (TB) infection.
Aabye, Aichelburg, Altet-Gómez, Andersen, Arend, Baba, Bakir, Bamford, Bartalesi, Bocchino, Brock, Brock, Carmona, Casas, Chee, Choi, Clark, Cobanoglu, Connell, Connell, Davies, Detjen, Dheda, Diel, Diel, Diel, Diel, Doherty, Domínguez, Domínguez, Domínguez, Ferrara, García-Gasalla, Gardam, Goletti, Higuchi, Hill, Horsburgh, Jafari, Jafari, Jafari, Janssens, Jasmer, Jones, José Domínguez Benítez, Kampmann, Karam, Kik, Kim, Kim, Kobashi, Kobashi, Kobashi, Lalvani, Lalvani, Lalvani, Lalvani, Lalvani, Latorre, Latorre, Leidl, Leung, Liebeschuetz, Lighter, Liu, Losi, Mandalakas, Markova, Martin, Matulis, Menzies, Menzies, Metcalfe, Miguel Santín Cerezales, Millington, Mori, Nicol, Nienhaus, Pai, Pai, Panes, Patel, Ponce de León, Raby, Rangaka, Richeldi, Richeldi, Rivas, Ruhwald, Santín, Sester, Stephan, Syed Ahamed Kabeer, Takahashi, Thomas, Trajman, Tsiouris, Van Zyl-Smit, Vassilopoulos, Vincenti, Wilkinson   +100 more
core   +2 more sources

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

A retrospective cohort study of patients treated with anti-tuberculous therapy for presumed ocular tuberculosis

Journal of Ophthalmic Inflammation and Infection, 2017
Background Uveitis involving the posterior segment is a significant and potentially blinding condition. The diagnosis and treatment of patients with uveitis associated with tuberculosis remains controversial, and commonly, patients are systemically well.
Erika Marie Damato, Sarah Dawson, Xiaoxuan Liu, Chandoshi Mukherjee, John Horsburgh, Alastair K. Denniston, Edward Moran, Martin Dedicoat, Philip Ian Murray   +8 more
doaj   +1 more source

Uloga testova otpuštanja interferona gama u nadzoru nad tuberkulozom [PDF]

, 2012
Tuberculosis is still one of the major global public health threats. Countries with low incidence must focus on exhausting the reservoir of future cases by preventing reactivation.
A Detjen, A Dyrhol-Riise, A Jurčev-Savičević, A Lalvani, A Mandalakas, A Naseer, A Nienhaus, A Pooran, A Seidler, A Veerapathran, A Zwerling, Anamarija Jurčev-Savičević, B Bergamini, B Linas, C Baker, C Denkinger, C Lange, C Lange, D Dosanjh, D Goletti, D Menzies, D Tripodi, E Bruzzese, E Kim, F Piana, F Ringshausen, G Mazurek, H Igari, H Rieder, I Pavić, Ivan Gudelj, J Broekmans, J Choi, J Lighter, J Torres Costa, J Torres Costa, K Ewer, K Higuchi, Kornelija Miše, M Madariaga, M Pai, M Pai, M Pai, M Pai, M Pai, M Pai, M Pai, M Sester, N Harada, R Diel, R Diel, R Diel, R Diel, R Diel, R Diel, R Van Zyl-Smit, S Lee, S Perry, T Connell, T. Mori, U Mack, Vera Katalinić-Janković, Y Kobashi   +62 more
core   +2 more sources

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Performance of Interferon-γ Release Assays in Patients with Mycobacterium kansasii Infection

Infection and Drug Resistance, 2022
Chun-Hai Gao,1 Yan-An Zhang,2,3 Mao-Shui Wang3– 5 1Department of Clinical Laboratory, Linyi People’s Hospital, Linyi, People’s Republic of China; 2Department of Cardiovascular Surgery, Shandong Public Health Clinical Center, Cheeloo College of Medicine ...
Gao CH, Zhang YA, Wang MS
doaj