Results 181 to 190 of about 260,978 (210)

Correction for Rodriguez-Hernandez et al., Microbiome-mediated incapacitation of interferon lambda production in the oral mucosa. [PDF]

Proc Natl Acad Sci U S A, 2022
europepmc   +1 more source

Interferon lambda receptor-1 isoforms differentially influence gene expression and HBV replication in stem cell-derived hepatocytes. [PDF]

Antiviral Res
Novotny LA, Evans JG, Guo H, Kappler CS, Meissner EG.   +4 more
europepmc   +1 more source

Gender-dependent multiple cross-phenotype association of interferon lambda genetic variants with peripheral blood profiles in healthy individuals. [PDF]

Mol Genet Genomic Med
Roy DG, Singh L, Chaturvedi HK, Chinnaswamy S.   +3 more
europepmc   +1 more source

The Pi Lambda Theta journal the official organ of Pi Lambda Theta

Pi Lambda Theta
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Genetics of the Human Interferon Lambda Region

Journal of Interferon and Cytokine Research, 2019
Humans are polymorphic in their ability to produce type-III interferons. Most individuals of African ancestry are genetically capable of generating all 4 type-III interferons (IFN-λ1, 2, 3, and 4), whereas the majority of individuals of European and Asian ancestry lack IFN-λ4 and thus can generate only IFN-λ1, 2, and 3.
Ludmila Prokunina-Olsson
exaly   +3 more sources

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Interferon Lambda and Liver Fibrosis

Journal of Interferon and Cytokine Research, 2019
Fibrosis is a highly conserved and coordinated wound healing response to injury. In the liver, injury is promoted by immune effector mechanisms that are common across various disease etiologies and even between organs such as lungs, kidneys, heart, and other organs.
Mohammed Eslam, Jacob George, Golo Ahlenstiel   +2 more
exaly   +4 more sources

Interferon Lambda: Modulating Immunity in Infectious Diseases [PDF]

Frontiers in Immunology, 2017
Interferon lambdas (IFN-λs; IFNL1-4) modulate immunity in the context of infections and autoimmune diseases, through a network of induced genes. IFN-λs act by binding to the heterodimeric IFN-λ receptor (IFNLR), activating a STAT phosphorylation-dependent signaling cascade.
Adrian Egli
exaly   +4 more sources

Lambda interferons in immunity and autoimmunity

Journal of Autoimmunity, 2019
Type I IFNs are well known players in immunity and autoimmunity. They induce potent innate and adaptive immune responses essential for mediating host defenses against viral and bacterial infections but also driving inflammation during chronic inflammatory and autoimmune diseases.
Stelios, Vlachiotis, Evangelos, Andreakos   +1 more
openaire   +2 more sources