Results 21 to 30 of about 10,723,036 (376)
Biology and therapeutic potential of interleukin-10
Journal of Experimental Medicine, 2019 The authors review the molecular mechanisms regulating IL-10 production and response and describe classic and novel functions of IL-10 in immune and non-immune cells.
M. Saraiva, P. Vieira, A. O’Garra
semanticscholar +1 more source
Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk [PDF]
, 2011 <p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p> <p><b>Methods and Results:</b> In the ...
Craen, A.J.M. de +11 more
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International Journal of Preventive Medicine, 2019 Background: Periimplant diseases are inflammatory diseases. Thus, the level of preinflammatory cytokines which has important role in the inflammation processes can consider as biomchemical markers for early diagnosis and prevention of periimplant ...
Shirin Zahra Farhad +2 more
doaj +1 more source
BMC Geriatrics, 2018 Background and objectives The pathophysiological mechanism of sarcopenia in the elderly has not yet been fully understood. Here, we aim to explore the relationship between sarcopenia and the inflammatory cytokine interleukin-6 (IL-6), and the anti ...
Yu-Dong Rong +4 more
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Comparison of spleen characterization and plasma levels of interleukin 6 and 10 in obese and healthy individuals [PDF]
Journal of Shahrekord University of Medical SciencesBackground and aims: Spleen is one of the organs that has great importance in Iranian traditional medicine due to its relationship with obesity. Therefore, in this study, we aim to investigate spleen characterization and plasma levels of interleukin 6 ...
Mahdis Tanzifi +4 more
doaj +1 more source
Expression of inflammation-related genes is associated with adipose tissue location in horses [PDF]
, 2013 Background : In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact of specific AT depots.
Bruynsteen, Lien +6 more
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Biology of interleukin-10 [PDF]
Cytokine & Growth Factor Reviews, 2010 Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes/macrophages and T cell subsets including Tr1, Treg, and Th1 cells. IL-10 acts through a transmembrane receptor complex, which is composed of IL-10R1 and IL-10R2, and regulates ...
Sabat R +6 more
openaire +2 more sources
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
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eLife, 2017 Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propria macrophage function during infant development in mice and whether macrophage-intrinsic IL10R signaling
Naresh S Redhu +16 more
doaj +1 more source
Blood concentrations of endothelin, interleukins 6 and 10 in men with diabetes mellitus
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 Background. Pathological activation of cytokines is one of the key links in the pathogenesis of diabetes mellitus (DM) and the development of its complications, in particular from the cardiovascular system.
E.V. Luchytskiy +4 more
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