Interleukin-17 Receptor D in Physiology, Inflammation and Cancer [PDF]
Frontiers in Oncology, 2021 Interleukin-17 receptor D (IL-17RD) is an evolutionarily conserved member of the IL-17 receptor family. Originally identified as a negative regulator of fibroblast growth factor (FGF) signaling under the name of Sef (Similar expression to FGF genes), IL ...
Charlotte Girondel +4 more
doaj +8 more sources
Endometrial senescence is mediated by interleukin 17 receptor B signaling [PDF]
Cell Communication and SignalingBackground We previously identified Il17RB, a member of the IL17 superfamily, as a candidate marker gene for endometrial aging. While IL17RB has been linked to inflammation and malignancies in several organ systems, its function in the endometrium has ...
Keiko Kawamura +9 more
doaj +4 more sources
Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling [PDF]
Cell Communication and Signaling, 2021 Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways .
Shivangi Pande +2 more
doaj +5 more sources
Interleukin 17 receptor A modulates monocyte subsets and macrophage generation in vivo. [PDF]
PLoS ONE, 2014 Interleukin (IL)-17A signaling via Interleukin 17 receptor A (Il17ra) contributes to the inflammatory host response by inducing recruitment of innate immune cells, but also plays a role in homeostatic neutrophilic granulocyte regulation.
Shuwang Ge +7 more
doaj +4 more sources
Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen +3 more
doaj +3 more sources
Correction: Endometrial senescence is mediated by interleukin 17 receptor B signaling [PDF]
Cell Communication and SignalingKeiko Kawamura +9 more
doaj +3 more sources
SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin-Proteasome-Mediated Degradation. [PDF]
Biomedicines, 2023 Interleukin-17 (IL-17) is a pro-inflammatory cytokine that participates in innate and adaptive immune responses and plays an important role in host defense, autoimmune diseases, tissue regeneration, metabolic regulation, and tumor progression. Post-translational modifications (PTMs) are crucial for protein function, stability, cellular localization ...
Jin B +6 more
europepmc +4 more sources
Impact of Adalimumab Treatment on Interleukin-17 and Interleukin-17 Receptor Expression in Skin and Synovium of Psoriatic Arthritis Patients with Mild Psoriasis [PDF]
Biomedicines, 2022 Interleukin (IL)-17 and tumor necrosis factor-alpha (TNF)-α are key players in psoriatic arthritis (PsA) pathogenesis. While both cytokines can be therapeutically targeted with beneficial clinical outcome, it is unclear whether inhibiting one cytokine ...
Janne W. Bolt +9 more
doaj +2 more sources
Interleukin-17 receptor antagonist reduces inflammatory response in experimental periodontitis
International Dental Journal, 2023 Aim or Purpose: Interleukin (IL)-17 is one of the inflammatory cytokines caused periodontitis and psoriasis. Psoriasis, a chronic inflammatory skin disease, treats with IL-17 receptor antagonist (brodalumab: BRD).
Dr Takenori Sato, Dr. Keisuke Handa
doaj +2 more sources
Downregulation of chicken interleukin-17 receptor A during Eimeria infection. [PDF]
Infect Immun, 2014 ABSTRACT Both interleukin-17A (IL-17A) and IL-17F are proinflammatory cytokines that have an important role in intestinal homeostasis via receptor signaling. These cytokines have been characterized in chickens, but very little is known about their receptors and their functional activity.
Kim WH +9 more
europepmc +4 more sources