Results 211 to 220 of about 582,539 (259)

Assessment of interleukin-18 gene polymorphism and serum levels in cutaneous lichen planus. [PDF]

Eur J Med Res
Doss RW, El-Rifaie AA, Roshdy AN, Sabry D.   +3 more
europepmc   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

Salivary interleukin-17A and interleukin-18 levels in patients with celiac disease and periodontitis. [PDF]

PeerJ
Madi M, Abdelsalam M, Elakel A, Zakaria O, AlGhamdi M, Alqahtani M, AlMuhaish L, Farooqi F, Alamri TA, Alhafid IA, Alzahrani IM, Alam AH, Alhashmi MT, Alasseri IA, AlQuorain AA, AlQuorain AA.   +15 more
europepmc   +1 more source

Serum levels of interleukin-18, CXCL9 and IFN-γ in Still's disease complicated by macrophage activation syndrome. [PDF]

Rheumatol Adv Pract
Turtsevich IZ, Gilmour KC, Hong Y, Eleftheriou D, Brogan PA.   +4 more
europepmc   +1 more source

Interleukin‑18 binding protein: Biological properties and roles in human and animal immune regulation (Review). [PDF]

Biomed Rep
Wang F.
europepmc   +1 more source

Monoclonal Antibodies Against Mature Interleukin-18 Ameliorate Colitis and Repair Goblet Cell Function. [PDF]

Dig Dis Sci
Mu J, Maeda K, Ohashi A, Urano T, Nariai Y, Kamino H, Nakamura M, Yamamura T, Sawada T, Ishikawa E, Murate K, Yamamoto K, Hirose T, Furukawa K, Fujishiro M, Kawashima H.   +15 more
europepmc   +1 more source

Interleukin-18 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility: An Umbrella Review of Meta-Analyses. [PDF]

J Immunol Res
Chen Y, Ye Y, Liu H, Luo Z, Li Q, Xie Q.
europepmc   +1 more source

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Interleukin-18 and stress

Brain Research Reviews, 2008
Interleukin-18 (IL-18) is a pro-inflammatory cytokine believed to play a role in a variety of conditions and diseases including infections, autoimmunity, cancer, diabetes and atherosclerosis. IL-18 is also a possible contributor to the sickness syndrome by inducing anorexia and sleep.
Shuei, Sugama, Bruno, Conti
openaire   +2 more sources

INTERLEUKIN 18 IN THE HEART

Shock, 2008
IL-18, originally termed as interferon gamma (IFN-gamma) inducing factor, is a proinflammatory cytokine that belongs to the IL-1 cytokine superfamily. IL-18 plays an important role in immune, infectious, and inflammatory diseases due to its induction of IFN-gamma.
Meijing, Wang, Troy A, Markel, Daniel R, Meldrum   +2 more
openaire   +2 more sources