Results 1 to 10 of about 540,906 (259)

Interleukin 1 Receptor-Like 1 Protein (ST2) is a Potential Biomarker for Cardiomyopathy in Duchenne Muscular Dystrophy [PDF]

open access: yesPediatric Cardiology, 2017
Duchenne muscular dystrophy (DMD) is a rare, fatal X-linked disorder characterized by the lack of dystrophin, a key sarcolemma muscle protein. Cardiac failure is a significant cause of death in DMD subjects. The purpose of our research was to identify potential cardiac serum biomarkers associated with DMD cardiomyopathy.
Julia Anderson   +4 more
openaire   +3 more sources

Study on the Mechanism of Budesonide in the Treatment of IgA Nephropathy Based on Network Pharmacology [PDF]

open access: yesZhongguo quanke yixue, 2023
Background IgA nephropathy (IgAN) is the most common primary glomerulonephritis in China and worldwide, approximately 25%-30% of patients will progress to end-stage renal disease within 20 years after diagnosis.
ZHANG Kang, ZHAO Tingting, ZHANG Bo, GAO Mengqi, LI Yuxi, WANG Shaopeng, ZHAO Wenjing
doaj   +1 more source

Identification and characterization of genome-wide resistance gene analogs (RGAs) of durian (Durio zibethinus L.)

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Background Durian (Durio zibethinus L.) is a tropical fruit crop which is popular in Southeast Asia but recently gaining popularity in other parts of the world. In this study, we analyzed the resistance gene analogs (RGAs) of durian through mining of the
Cris Q. Cortaga   +3 more
doaj   +1 more source

Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage

open access: yesVirulence, 2021
Thousands of human deaths occur annually due to Japanese encephalitis (JE), caused by Japanese encephalitis virus. During the virus infection of the central nervous system, reactive gliosis, uncontrolled inflammatory response, and neuronal cell death are
Usama Ashraf   +5 more
doaj   +1 more source

Cardiovascular disease-linked plasma proteins are mainly associated with lung volume

open access: yesERJ Open Research, 2023
Background Epidemiological studies have shown that impaired lung function is common and associated with increased risk of cardiovascular disease. Increased levels of several inflammatory and cardiovascular disease-related plasma proteins have been ...
Andreas Rydell   +14 more
doaj   +1 more source

IL1RAPL1 associated with mental retardation and autism regulates the formation and stabilization of glutamatergic synapses of cortical neurons through RhoA signaling pathway. [PDF]

open access: yesPLoS ONE, 2013
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is associated with X-linked mental retardation and autism spectrum disorder. We found that IL1RAPL1 regulates synapse formation of cortical neurons.
Takashi Hayashi   +4 more
doaj   +1 more source

Effects of IL-38 on Macrophages and Myocardial Ischemic Injury

open access: yesFrontiers in Immunology, 2022
Macrophages play an important role in clearing necrotic myocardial tissues, myocardial ischemia–reperfusion injury, and ventricular remodeling after myocardial infarction.
Zhiyang Li   +10 more
doaj   +1 more source

Role of the NLRP3 inflammasome in cancer

open access: yesMolecular Cancer, 2018
Inflammasomes are large intracellular multi-protein signalling complexes that are formed in the cytosolic compartment as an inflammatory immune response to endogenous danger signals. The formation of the inflammasome enables activation of an inflammatory
Maryam Moossavi   +4 more
doaj   +1 more source

Identification and function of myeloid differentiation factor 88 (MyD88) in Litopenaeus vannamei. [PDF]

open access: yesPLoS ONE, 2012
Myeloid differentiation factor 88 (MyD88) is a universal and essential signaling protein in Toll-like receptor/interleukin-1 receptor-induced activation of nuclear factor-kappa B.
Shuang Zhang   +7 more
doaj   +1 more source

Host genome polymorphisms and tuberculosis infection: What we have to say?

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2014
Several epidemiology studies suggest that host genetic factors play important roles in susceptibility, protection and progression of tuberculosis infection.
Said Alfin Khalilullah   +5 more
doaj   +1 more source

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