Results 91 to 100 of about 4,841,277 (301)

More stories on Th17 cells [PDF]

, 2009
For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain most of the phenomena related to adaptive immunity.
A Awasthi, A Billiau, A Brustle, A Coutinho, A Laurence, AF Sheibanie, Alexandre S Basso, AR de Lera, B Guo, B Oesch-Bartlomowicz, B Oppmann, B Stockinger, BM Segal, C Dong, C Infante-Duarte, CA Murphy, CF Anderson, CL Langrish, CM Sun, CR Parish, CR Parish, CR Parish, CS Hsieh, D Jankovic, D Mucida, D Mucida, D Mucida, Daniel Mucida, DC Fitzgerald, DJ Cher, DJ Cua, E Bettelli, E Bettelli, E Bettelli, E Volpe, EB Samoilova, EH Tran, EV Acosta-Rodriguez, EV Hestermann, F Ohtake, F Ramirez, F Schambach, FJ Quintana, FY Liew, FY Liew, G Moller, GX Zhang, H Park, HG Evans, HH Hofstetter, Hilde Cheroutre, I Apostolou, II Ivanov, II Ivanov, II Ivanov, IM Irmler, J Hu-Li, J Moisan, J Rengarajan, J Si, J Yang, JA Voorthuis, JD Chen, JD Fontenot, JL Coombes, JP Leonard, JS Stumhofer, JS Stumhofer, K Atarashi, K Ichiyama, KA Bush, KA Murphy, KI Happel, KM Elias, KM Murphy, L Saurer, L Steinman, L Yang, L Zhou, L Zhou, LE Harrington, M Batten, M Krakowski, M Lochner, M Raffatellu, M Rocken, M Schnurr, M Veldhoen, M Veldhoen, M Veldhoen, MA Curotto De Lafaille, MA Curotto de Lafaille, MA Kleinschek, MC Fantini, MG Kattah, MJ McGeachy, MJ McGeachy, MO Li, MP Das, MS Denison, N Manel, P Angkasekwinai, P Tai, P Ye, PR Mangan, R Nurieva, RA Kastelein, RL Coffman, RL Coffman, S Aggarwal, S Nakae, S Sakaguchi, S Uematsu, S Xiao, S Zhang, SA Khader, SG Zheng, SG Zheng, SJ Szabo, SL Reiner, T Korn, T Owaki, T Owaki, TL Denning, TR Mosmann, TR Mosmann, TS Davidson, TT Duong, W Chen, XO Yang, XO Yang, XO Yang, Y Carrier, Y Komiyama, Y Okuda, YH Wang, Z Chen   +136 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. [PDF]

, 2012
International audienceABSTRACT: The Blood--brain barrier (BBB), present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and ...
Artus, Cédric, Couraud, Pierre-Olivier, Ganeshamoorthy, Kayathiri, Glacial, Fabienne, Luissint, Anny-Claude   +4 more
core   +4 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair. [PDF]

, 2015
Helminth parasites can cause considerable damage when migrating through host tissues, thus making rapid tissue repair imperative to prevent bleeding and bacterial dissemination particularly during enteric infection.
Bürgi, J., Esser-von Bieren, J., Harris, N.L., Marsland, B.J., Sutherland, D.B., Urban, J.F., Verbeek, J.S., Volpe, B.   +7 more
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Ezrin/radixin/moesin proteins differentially regulate endothelial hyperpermeability after thrombin [PDF]

, 2018
L
Adyshev, Djanybek M., Dudek, Steven, Garcia, Joe G. N., Kim, Kyung-mi, Kovács-Kása, Anita, Ma, Shwu-Fan, Moldobaeva, Nurgul, Verin, Alexander   +7 more
core   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

IL-25 promotes trophoblast proliferation and invasion via binding with IL-17RB and associated with PE

Hypertension in Pregnancy, 2021
Introduction: Interleukin-25 is a Th2 interleukin and has been shown to influence cell behavior. This study aims to illustrate its affection on extravillous trophoblasts function and association with PE.
Siyu Liu, Yi Sun, Yao Tang, Rong Hu, Qiongjie Zhou, Xiaotian Li   +5 more
doaj   +1 more source