Results 121 to 130 of about 4,322,877 (234)
Total synthesis of glycosylated interleukin-25 via integrated chemical ligations
, 2017 published_or_final_version ; Chemistry ; Doctoral ; Doctor of ...
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Advanced Healthcare Materials, EarlyView.Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi +10 more
wiley +1 more source
Interleukin-25 induces allergic inflammation
Journal of Japan Society of Immunology & Allergology in Otolaryngology, 2012 Hideaki Kouzaki, Takeshi Shimizu
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Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu +10 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen +9 more
wiley +1 more source
IL‐2 Free Expansion of T Cells with Immunofilaments
Advanced Healthcare Materials, EarlyView.Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck +4 more
wiley +1 more source
MOESM1 of Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma
, 2018 Additional file 1: Figure S1. Sequential Multi-gating strategy: to identify hemopoietic progenitor cells (HPC: CD45+CD34+) and Eosinophil-lineage committed progenitors (EoP; CD45+CD34+CD125+) in blood using FlowJo software on a LSRII. FlowJo plots of specific antibody and isotype control antibody for IL-17RA and IL-17RB on (A) HPC and (B) EoP with a 98%
Tang, Wei +10 more
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Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Advanced Healthcare Materials, EarlyView.This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source