Results 31 to 40 of about 54,526,142 (249)

Mathematical modeling of Interleukin-35 promoting tumor growth and angiogenesis.

, 2014
Interleukin-35 (IL-35), a cytokine from the Interleukin-12 cytokine family, has been considered as an anti-inflammatory cytokine which promotes tumor progression and tumor immune evasion. It has also been demonstrated that IL-35 is secreted by regulatory
Kang-Ling Liao, Xue-Feng Bai, and Avner Friedman, Kang-Ling Liao, Avner Friedman, Bai Xue-Feng, Liao Kang-Ling, Xue-Feng Bai, Friedman Avner   +6 more
core   +1 more source

cDNA Cloning of Biologically Active Chicken Interleukin-18 [PDF]

, 2000
By searching a chicken EST database, we identified a cDNA clone that appeared to contain the entire open reading frame (ORF) of chicken interleukin-18 (ChIL-18).
Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Baeuerle, Patrick A., Kaspers, Bernd, Kirsten Schneider, Schneider, Kirsten, Baeuerle, Daniela, Daniela Baeuerle, Kirsten C. Weining, Puehler, Florian, Elvers, Sandra, Weining, Kirsten C., Florian Puehler, Sandra Elvers, Bernd Kaspers   +15 more
core   +1 more source

Mathematical modeling of interleukin-27 induction of anti-tumor T cells response. [PDF]

, 2014
Interleukin-12 is a pro-inflammatory cytokine which promotes Th1 and cytotoxic T lymphocyte activities, such as Interferon-[Formula: see text] secretion. For this reason Interleukin-12 could be a powerful therapeutic agent for cancer treatment.
Kang-Ling Liao, Xue-Feng Bai, and Avner Friedman, Kang-Ling Liao, Avner Friedman, Xue-Feng Bai (333686), Bai Xue-Feng, Liao Kang-Ling, Xue-Feng Bai, Friedman Avner, Kang-Ling Liao (535938), Avner Friedman (54903)   +9 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Interleukin-35 on B cell and T cell induction and regulation

Journal of Inflammation, 2017
Interleukin (IL)-35 is a relatively newly discovered member of IL-12 cytokine family that is unique in that it is a dimer formed by two subunits. The review documents the structure, secretion and signal transduction of IL-35, the regulation effect of IL ...
Ai Huang, Lin Cheng, Miao He, Jun Nie, Jianjun Wang, Ke Jiang   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Correlation between interleukin 35 or interleukin 37 and clinicopathology and prognosis of colorectal cancer

Zhongguo aizheng zazhi, 2020
Background and purpose: Colorectal cancer (CRC) is the third most common cancer in the world. Recently, it is suggested that interleukin (IL)-35 and/or IL-37 are associated with CRC, but the precise underlying mechanism has not been fully explored.
陈飞儿, 张　凤, 谈振宇, 夏庆华, 包士三, 陶　琨, 董志恒   +6 more
doaj  

Pomegranate extract supplementation improves lung function parameters and IL-35 expression in participants with mild and moderate persistent allergic asthma: A randomized, double-blind, placebo-controlled trial

Frontiers in Nutrition, 2022
Existing asthma treatments are associated with side effects and limitations, which has led to an interest in alternative and complementary therapies. Given the anti-inflammatory properties of pomegranate, the present study aimed to determine the impact ...
Zainab Shateri, Zainab Shateri, Zainab Shateri, Seyed Ahmad Hosseini, Seyed Ahmad Hosseini, Farhad Abolnezhadian, Elham Maraghi, Maryam Haddadzadeh Shoushtari, Marzie Zilaee, Marzie Zilaee   +9 more
doaj   +1 more source

The effects of anti-interleukin-5 on SABA rescue use.

, 2016
The effects of anti-interleukin-5 on SABA rescue use.
Ting Liu (45625), Fa-Ping Wang (3358667), Hui Mao (115181), Zhu Lan (3358673), Su-Yun Li (3358670)   +4 more
core   +1 more source

Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]

, 2003
Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda, Zsuzsa Gyorfy, Duda, Erno, Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Annette Ohnemus, Kaspers, Bernd, Gyorfy, Zsuzsa, Ohnemus, Annette, Bernd Kaspers   +10 more
core   +1 more source