Interleukin-35 as a key immunoregulatory mediator in steroid-hyporesponsive severe asthma [PDF]
Frontiers in ImmunologySevere asthma remains a major unmet clinical challenge, largely due to corticosteroid hyporesponsiveness in a subset of patients. Despite high-dose inhaled or systemic corticosteroids and targeted biologics, chronic airway inflammation often persists ...
Jehan Al-Matouq +10 more
doaj +2 more sources
Association Between Interleukin 35 Gene Single Nucleotide Polymorphisms and the Uveitis Immune Status in a Chinese Han Population [PDF]
Frontiers in Immunology, 2021 Autoimmune uveitis is characterized by immune disorders of the eyes and the whole body and is often recurrent in young adults, but its pathogenesis is still unclear.
Meng Feng +13 more
doaj +2 more sources
Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats. [PDF]
Saudi J Biol Sci, 2023 Paracetamol (PAR) is a commonly used antipyretic and analgesic agent, but its excessive usage can induce liver damage and major health consequences.
Abduh MS +6 more
europepmc +2 more sources
Urine and serum interleukin 35 as potential biomarkers of lupus nephritis [PDF]
Central European Journal of Immunology, 2021 Mary Atef Nassif
doaj +2 more sources
Expression of interleukin-35 and type 2 cytokines in children with acute allergic asthma [PDF]
Iranian Journal of Immunology, 2021 Background: Allergic asthma is believed to be a T helper 2 cell (Th2) preponderant response caused by airway hyper-responsiveness. Interleukin-35 (IL-35) is a newly discovered anti-inflammatory cytokine.
Zhangqiao Cai, Xuxia He, Jing Yang
doaj +1 more source
Interleukin-35 Levels in Patients with Stable Coronary Artery Disease
, 2022 Background It has been shown that interleukin-35 (IL-35) subunits are strongly expressed in atherosclerotic plaques in humans. Therefore, it is considered to play a role in atherosclerosis. Objectives In this study, IL-35 levels were compared with the
Bulent Demir (12698615) +7 more
core +1 more source
Frontiers in Immunology, 2021 Chronic hepatitis B virus (HBV) infection induces dysfunction of immune response and chronic liver damage. However, the mechanisms that account for HBV-related hepatocellular carcinoma (HCC) are poorly understood.
Qian Zhang +4 more
doaj +1 more source
BMC Immunology, 2020 Background Interleukin-35 (IL-35) is a newly identified IL-12 cytokine family member, which regulates the activity of immune cells in infectious diseases and autoimmune disorders.
Haijian Xing, Gang Tian
doaj +1 more source
Effect of nonsurgical periodontal therapy on interleukin-35 level in gingival crevicular fluid
SRM Journal of Research in Dental Sciences, 2023 Background: Clinical attachment level (CAL), alveolar bone loss, and periodontal pockets constitute the major signs of periodontitis. The interaction between the host and the bacteria that forms a biofilm on the tooth surface is one of the major ...
Ashwini Jadhav +3 more
doaj +1 more source
Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release [PDF]
, 2002 Background: Angiotensin 1 converting enzyme (ACE) inhibitors reduce morbidity and mortality after coronary artery bypass graft surgery (CABG). This benefit may result from an anti- inflammatory action.
Humphries, S.E. +5 more
core +8 more sources