Results 61 to 70 of about 54,526,142 (249)

Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV₁.

, 2016
Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV1.
Ting Liu (45625), Fa-Ping Wang (3358667), Hui Mao (115181), Zhu Lan (3358673), Su-Yun Li (3358670)   +4 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Assessment of the Interleukin-32 and Interleukin-35 Levels in the Circulation of Hashimoto’s Thyroiditis Patients

Medical Journal of Babylon
Background: Hashimoto’s thyroiditis (HT) is a more common autoimmune disease causing chronic thyroid gland inflammation with many genetic and environmental uncertain etiologies. The main characteristic of HT is the loss of thyroid tissue as a result of a
Ahmed Hadi Saeed Al-Khafaji, Jawad Kadhim Tarrad Al-Khafaj, Abdulnabi J. Abid   +2 more
doaj   +1 more source

Correlation of Preoperative NLR, IL-35 and MTA2 with Postoperative Recurrence and Metastasis in Patients with Prostate Cancer

Guoji laonian yixue zazhi
Objective To investigate the predictive value of preoperative neutrophil to lymphocyte ratio (NLR), interleukin-35 (IL-35) and metastasis-associated protein 2 (MTA2) for postoperative recurrence and metastasis in patients with prostate cancer.
Ning An, Jiaqi Cheng, Hongyan He, Xiaolu Cheng, Zengxi Zhao   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding [PDF]

, 2009
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk factors that include hypertension and hyperlipidaemia, influenced by diet.
Dower, S., Zoe Brookes, Nicholas J Alp, Francis, Sheila, Steven Dower, David C Crossman, Brookes, Zoe, Francis, S., Shaw, Gary, Shaw, G., Crossman, D.C., Gary Shaw, Sheila Francis, Graham, Delyth, Brookes, Z., Alp, N.J., Crossman, David C., Chamberlain, J., Delyth Graham, Dower, Steven, Graham, D., Xu, A., Janet Chamberlain, Alp, Nicholas J., Xu, Aimin, Chamberlain, Janet   +25 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Assessment of the immunomodulatory cytokines interleukin-35, interleukin-10, and transforming growth factor-β in patients with idiopathic immune thrombocytopenia purpura on treatment with romiplostim: A cross-sectional analysis

Iraqi Journal of Hematology
BACKGROUND: Idiopathic immune thrombocytopenia purpura is an autoimmune bleeding disorder that accounts for approximately one-third of clinical hemorrhagic diseases.
Aisha Muthanna Shanshal, Samer Imad Mohammed, Bassam Francis Matti   +2 more
doaj   +1 more source

Serum Interleukin-35 Level in Correlation with T Regulatory and T helper-17 Cells Frequency in Chronic Viral Hepatitis C Patients

, 2020
Interleukin-35 (IL-35), secreted mainly by T-regulatory cells (T-regs), has been considered to have immunosuppressive actions in many auto-immune diseases and tumors.
Ossama A. Ahmed, Heba I. Aly, Dina M. Erfan, Safaa S. Abo-Elnour, Sherine E. Bendary, Amira E. Abdelhamid   +5 more
core   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source