Results 11 to 20 of about 732,329 (269)
Interleukin-1 and interleukin-1 antagonism [PDF]
Blood, 1991 The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes.
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ROLE OF INTERLEUKIN 1 IN THE DEVELOPMENT OF HUMAN DISEASES
Научно-практическая ревматология, 2016 According to the predominant mechanisms of immunity activation, human inflammatory diseases are divided into two main categories: autoimmune and autoinflammatory ones.
E. L. Nasonov, M. S. Eliseev
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Potential biochemical markers of chronic bronchitis
Бюллетень сибирской медицины, 2021 The review systematizes modern data on the biochemical markers that can clarify the nature and the course of chronic bronchitis. The article describes markers associated with bronchopulmonary pathology, such as tumor necrosis factor alpha (TNFα ...
E. A. Kurtukov, Yu. I. Ragino
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Role of interleukin 1 in the development of atherosclerosis
Научно-практическая ревматология, 2019 Atherosclerosis is now considered as chronic inflammatory vascular disease connected to «pathological» activation of innate and adaptive immunity, characterized by lipid deposition, leukocyte infiltration and proliferation of vascular smooth muscle cells.
E. L. Nasonov, T. V. Popkova
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Therapy with canakinumab for adult-onset still's disease
Научно-практическая ревматология, 2019 Still's disease in children (systemic-onset juvenile idiopathic arthritis, SoJIA) and in adults (adult-onset Still's disease) are considered as non-familial systemic autoinflammatory diseases of unknown etiology driven by similar immunopathogenetic ...
E. L. Nasonov
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Innate immune activation as cofactor in pemphigus disease manifestation
Frontiers in Immunology, 2022 Molecular mechanisms underlying auto-antibody-induced acantholysis in pemphigus vulgaris are subject of current research to date. To decipher the discrepancy between ubiquitous antibody binding to the epidermal desmosomes, but discontinuous disease ...
Ramona A. Eichkorn +7 more
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The role of interleukin 1 in the development of human diseases
Научно-практическая ревматология, 2019 Human immuno-inflammatory diseases (IID), depending on the predominant mechanisms of immune activation, are divided into two main categories: autoimmune and autoinflammatory.
E. L. Nasonov
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Interleukin-1 and Interleukin-6 in Psoriasis
Journal of Investigative Dermatology, 1990 We report on the levels of expression of IL-1 and IL-6 in skin from psoriasis patients. Different approaches were pursued. Initially, the levels of IL-1 beta and IL-6 were measured in suction blister fluid from lesional and uninvolved skin from psoriasis patients, using a sensitive enzyme-linked immunoabsorbent assay (ELISA) and bio-assay.
Prens, Errol P. +6 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
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Научно-практическая ревматология, 2022 According to modern concepts, human immune-mediated inflammatory diseases (IMIDs), depending on the prevailing mechanisms of immunopathogenesis, are divided into two main categories – autoimmune and autoinflammatory.At the same time, both autoimmune and ...
E. L. Nasonov, M. Yu. Samsonov
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