Results 31 to 40 of about 4,886,092 (271)
Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration. [PDF]
Sci Adv, 2021 The cytokine interleukin-11 promotes regeneration and limits scar formation in multiple zebrafish tissues after injury.
Allanki S +10 more
europepmc +2 more sources
Cells, 2023 Granulosa cells (GCs) are essential for follicular growth, oocyte maturation, and steroidogenesis in the ovaries. Interleukin (IL)-11 is known to play a crucial role in the decidualization of the uterus, however, the expression of the IL-11 system (IL-11,
Hanxiao Wu +8 more
doaj +1 more source
IL11 activates the placental inflammasome to drive preeclampsia
Frontiers in Immunology, 2023 IntroductionPreeclampsia is a life-threatening disorder of pregnancy unique to humans. Interleukin (IL)11 is elevated in serum from pregnancies that subsequently develop early-onset preeclampsia and pharmacological elevation of IL11 in pregnant mice ...
Ellen Menkhorst +24 more
doaj +1 more source
Nature Communications, 2021 Interleukin (IL)-11 is a member of the IL-6 family of cytokines and is involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11+) cells are not fully understood.
T. Nishina +22 more
semanticscholar +1 more source
The biology of interleukin 11 [PDF]
STEM CELLS, 1996 Interleukin 11 (IL-11) is a multifunctional cytokine which may play a role in regulating the growth and development of cells in both the hematopoietic and lymphoid systems. IL-11 activity was originally detected in the conditioned medium of a primate bone marrow stromal cell line, and the human cDNA was cloned from a human fetal lung fibroblast cell ...
S, Neben, K, Turner
openaire +2 more sources
The FASEB Journal, 2021 Interleukin‐11 (IL‐11) is a pleiotropic cytokine with both pro‐ and anti‐inflammatory properties. It activates its target cells via binding to the membrane‐bound IL‐11 receptor (IL‐11R), which then recruits a homodimer of the ubiquitously expressed ...
L. Koch +7 more
semanticscholar +1 more source
The International Journal of Biochemistry & Cell Biology, 1997 Interleukin-11 (IL-11) is an IL-6-type cytokine that is produced by a variety of stromal cells including fibroblasts, epithelial cells and osteoblasts. It binds to a multimeric receptor complex which contains an IL-11-specific alpha subunit and a promiscuous 130 kDa beta subunit (gp130). IL-11 stimulates multiple aspects of hematopoiesis and hepatocyte
S X, Leng, J A, Elias
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Periodontal manifestations as related to the cytokines in the gingival crevicular fluid
Indian Journal of Dental Sciences, 2021 Backround: Periodontal diseases are classified into different categories based on the clinical symptoms and related to these there can be changes in the cytokine levels in the connective tissue and elaboration of these in the gingival crevicular fluid ...
Nymphea Pandit, Neeta Bhavsar
doaj +1 more source
Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway. [PDF]
Exp Mol Med, 2020 Interleukin (IL)-11 evolved as part of the innate immune response. In the human lung, IL-11 upregulation has been associated with viral infections and a range of fibroinflammatory diseases, including idiopathic pulmonary fibrosis.
Ng B, Cook SA, Schafer S.
europepmc +2 more sources