Results 41 to 50 of about 57,029,053 (268)

Interleukin-18 [PDF]

, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B., Robertson, S.E., Gracie, J.A.   +2 more
core   +1 more source

Interleukin-6 level in pediatric patients with COVID-19.

, 2023
Interleukin-6 level in pediatric patients with COVID-19.
Bahrul Fikri (17296062), Sitti Aizah Lawang (17296056), Amiruddin Laompo (17296053), Nadirah Rasyid Ridha (17296059), Syarifuddin Rauf (17296050), Muhammad Nasrum Massi (17296065), Idham Jaya Ganda (17296044), Try Kartika Eka Putri (17296047), Ninny Meutia Pelupessy (8918090)   +8 more
core   +1 more source

Transmembrane protein TMEM184B is necessary for interleukin-31-induced itch. [PDF]

Pain, 2022
Abstract Nociceptive and pruriceptive neurons in the dorsal root ganglia (DRG) convey sensations of pain and itch to the spinal cord, respectively. One subtype of mature DRG neurons, comprising 6% to 8% of neurons in the ganglia, is responsible for sensing mediators of acute itch and atopic dermatitis, including the cytokine IL-31.
Larsen EG, Cho TS, McBride ML, Feng J, Manivannan B, Madura C, Klein NE, Wright EB, Wickstead ES, Garcia-Verdugo HD, Jarvis C, Khanna R, Hu H, Largent-Milnes TM, Bhattacharya MRC.   +14 more
europepmc   +3 more sources

Effect of interleukin-31 on septic shock through regulating inflammasomes and interleukin-1β. [PDF]

Exp Ther Med, 2018
Sepsis with severe systemic inflammation remains a great challenge for the intensive care unit in clinics. Although biomarkers have been identified to diagnose, monitor and predict these syndromes, novel therapeutic approaches are required for the amelioration of symptoms of sepsis and septic shock.
Gu X, Wei C, Zhu X, Lu F, Sheng B, Zang X.   +5 more
europepmc   +4 more sources

Itch in dermatomyositis: the role of increased skin interleukin-31. [PDF]

Br J Dermatol, 2018
Interleukin (IL)-31 is implicated in pruritus associated with pruritic skin diseases like atopic dermatitis. Although pruritus is a prominent feature in dermatomyositis (DM), few studies have evaluated the pathogenesis of DM-associated itch.To establish the prevalence of itch in DM, and to investigate the role of IL-31 in DM-related itch.Pruritus and ...
Kim HJ, Zeidi M, Bonciani D, Pena SM, Tiao J, Sahu S, Werth VP.   +6 more
europepmc   +4 more sources

Detection of Interleukin-2 and Interleukin-31 among Patients with Uremic Pruritus

Indian Journal of Forensic Medicine & Toxicology, 2021
Uremic pruritus is a form of chronic itching that affects patients with advanced end-stage renal disease. Itis one of the most common symptoms in patients with end-stage renal disease, with approximately 60–90percent of patients on hemodialysis (HD) experiencing it.
null Hiba Mohammed Jasim, null Ismail Ibrahim Latif, null Nabeel Khalid Al Wandi   +2 more
openaire   +2 more sources

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem, Herrmann, Eva, Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Rudloff, Ina, Bernd Kronenberger, Waidmann, Oliver, Albrecht Piiper, Pfeilschifter, Josef (Prof. Dr.), Piiper, Albrecht, Heiko Mühl, Filmann, Natalie, Ina Rudloff, Malte Bachmann, Eva Herrmann, Josef Pfeilschifter, Lisa Kapper, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Mühl, Heiko, Natalie Filmann, Zeuzem, Stefan, Kronenberger Bernd, Brunner Friederike, Filmann Natalie, Kapper Lisa, Herrmann Eva, Zeuzem Stefan, Mühl Heiko, Rudloff Ina, Piiper Albrecht, Waidmann Oliver, Bachmann Malte, Pfeilschifter Josef   +35 more
core   +2 more sources

Interleukin-6 levels in the control and AAA groups.

, 2023
There was no significant difference in plasma levels of IL-6 between groups (P = .17). AAA, abdominal aortic aneurysm; IL-6, interleukin-6.
Lenka Maliskova (8781746), Robert L. Raffai (12633072), Shant M. Vartanian (14614693), Adam Z. Oskowitz (14614696), Andrea J. Barczak (782932), Laura Bouchareychas (3493793), Michael S. Conte (12160976), Joshua D. Rudolph (14614690), Phat Duong (5718677), Jose L. Lopez (14614678), Tuan Anh Phu (14614684), Christina R. Kuhrau (14614687), Pei-Yu Lin (3370841), Walter L. Eckalbar (9243670), Joel L. Ramirez (14614681)   +14 more
core   +1 more source

Evaluation of the role of interleukin-31 in inflammatory acne vulgaris: a case–control study

Journal of the Egyptian Women’s Dermatologic Society, 2020
Background Acne vulgaris (AV) is a chronic inflammatory disease with multifactorial etiology and a significant psychological disability. Inflammation is a fundamental process in the early and late stage of acne.
Shahira A Ramadan, Dalia M Abdel Halim, Rofaida El-Naggar, Nahed M Ibrahim, Marwa S El-Mesidy   +4 more
doaj   +1 more source

Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a studyResearch in context

EClinicalMedicine, 2023
Summary: Background: Prurigo nodularis is a chronic skin disease characterised by intensely pruritic, hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the beta subunit of the oncostatin M receptor, inhibiting signalling of both
Howard Sofen, Robert Bissonnette, Gil Yosipovitch, Jonathan I. Silverberg, Stephen Tyring, Wei Jing Loo, Matthew Zook, Mark Lee, Liangxing Zou, Guang-Liang Jiang, John F. Paolini   +10 more
doaj   +1 more source