Results 11 to 20 of about 1,103,478 (297)

Interleukin 6: friend or foe in diabetic nephropathy? [PDF]

Archives of Medical Science
Introduction This study aimed to investigate the relationship between serum cytokine levels, particularly interleukin 6 (IL-6), and diabetic nephropathy (DN) in patients with type 1 (T1D) and type 2 diabetes (T2D). Material and methods A cross-sectional
Renad M. Alhamawi, Walaa Mohammedsaeed, Maha Aljumaa   +2 more
doaj   +2 more sources

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background Sepsis and inflammation can cause intensive care unit‐acquired weakness (ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 signalling involves the glycoprotein 130 (gp130) receptor and the JAK/STAT‐pathway,
Lukas Zanders, Melanie Kny, Alexander Hahn, Sibylle Schmidt, Sebastian Wundersitz, Mihail Todiras, Ines Lahmann, Arnab Bandyopadhyay, Tobias Wollersheim, Lars Kaderali, Friedrich C. Luft, Carmen Birchmeier, Steffen Weber‐Carstens, Jens Fielitz   +13 more
doaj   +1 more source

Interleukin-6 Promoter Haplotypes and Interleukin-6 Cytokine Responses [PDF]

Shock, 2003
Genetic variations contribute to differences in the inflammatory response and are markers for disease risk and outcomes. We studied three single-nucleotide polymorphisms (-597 G-->A, -572 G-->C, and -174 G-->C) in the IL-6 promoter to determine associations with ex vivo LPS-stimulated IL-6 production by leukocytes.
Fernando A, Rivera-Chavez, Dixie L, Peters-Hybki, Robert C, Barber, Grant E, O'Keefe   +3 more
openaire   +2 more sources

Interleukin-6, age, and corpus callosum integrity. [PDF]

, 2014
The contribution of inflammation to deleterious aging outcomes is increasingly recognized; however, little is known about the complex relationship between interleukin-6 (IL-6) and brain structure, or how this association might change with increasing age.
Bettcher, Brianne M, Busovaca, Edgar, Dutt, Shubir, Green, Ralph, Kramer, Joel H, Lobach, Iryna V, Miller, Bruce L, Miller, Joshua W, Neuhaus, John, Patel, Nihar, Rosen, Howard J, Walsh, Christine M, Watson, Christa L, Yaffe, Kristine   +13 more
core   +6 more sources

Repurposing Interleukin-6 Inhibitors to Combat COVID-19. [PDF]

, 2020
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a pandemic with major implications across the world. One of the most frequent causes of death from SARS-CoV-2 is fatal pneumonia from coronavirus disease 2019 (COVID-19), which is associated
Kato, Shumei, Kurzrock, Razelle
core   +1 more source

Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome

Mediators of Inflammation, 2006
The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers ...
Daria Simcic, Sonja Pezelj-Ribaric, Renata Gržic, Jelena Horvat, Gordana Brumini, Miranda Muhvic-Urek   +5 more
doaj   +2 more sources

Correlation Between Interleukin 6 and Interleukin 10 in Acute Myocardial Infarction

Biomolecules & Biomedicine, 2009
The aim of this study was to analyze (i) ratios between pro-inflammatory cytokines interleukin 6 (IL-6), interleukin 1 (IL-1), tumour necrosis factor α (TNF-α) and anti-inflammatory cytokine interleukin 10 (IL-10) in patients with acute myocardial ...
Larisa Dizdarević-Hudić, Zumreta Kušljugić, Fahir Baraković, Selmira Brkić, Damir Sabitović, Elmir Jahić, Maida Isabegović, Elnur Smajić, Igor Hudić, Katarina Divković   +9 more
doaj   +1 more source

Management of patients with rheumatoid arthritis in real clinical practice: Switching from interleukin 6 receptor inhibitors to interleukin 6 inhibitor (olokizumab)

Научно-практическая ревматология, 2023
Aim. Switching to another biologic with the same mode of action provides greater opportunity for long-term management of patients with rheumatoid arthritis (RA).
A. A. Baranov, I. B. Vinogradova, O. N. Anoshenkova, O. V. Antipova, E. A. Bogdanova, Y. Y. Grabovetskaya, E. P. Ilivanova, A. N. Kalyagin, I. N. Kushnir, N. A. Lapkina, M. V. Mokrousova, O. B. Nesmeyanova, N. M. Nikitina, P. A. Shesternya, N. V. Yudina, E. Feist, E. L. Nasonov   +16 more
doaj   +1 more source

Paraneoplastic thrombocytosis in ovarian cancer [PDF]

, 2012
<p>Background: The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that platelets play in abetting cancer growth are unclear.</p> <p>Methods: We analyzed clinical data on 619 patients with epithelial ...
Akl EA, Alpa M. Nick, Angela F. Drew, Anil K. Sood, Bulent Ozpolat, Chad V. Pecot, Charles N. Landen, Diana Urbauer, Donald Lamkin, Edward H. Ahn, Erin R. King, Frances Balkwill, Francisca Gushiken, Gabriel Lopez-Berestein, Guillermo N. Armaiz-Pena, Hannah Gershenson, Hee Dong Han, Hernan G. Vasquez, Iain A. McNeish, Ibrahim Tekedereli, Jermaine Coward, Justin Bottsford-Miller, Katherine Collins, Koen DeGeest, Koji Matsuo, Mian M.K. Shahzad, Michael T. Deavers, Rajesha Rupaimoole, Rebecca L. Stone, Riess L, Rui Wang, Susan K. Lutgendorf, Vahid Afshar-Kharghan, Virginia K. Bond, Wah Chiu, Wei Hu   +35 more
core   +1 more source

Salivary Interleukin 6 and Sialic acid in Periodontitis

Brazilian Journal of Oral Sciences, 2018
Aim: Periodontitis is the major multi –factorial chronic infectious oral diseases in dentate people. Sialic acid regulates innate immunity response that release cytokines.
Jwan Ibrahim Jawzali
doaj   +1 more source