Results 21 to 30 of about 58,497 (228)
Cells, 2016 Intermediate filaments together with actin filaments and microtubules form the cytoskeleton, which is a complex and highly dynamic 3D network. Intermediate filaments are the major mechanical stress protectors but also affect cell growth, differentiation,
Nicole Schwarz, Rudolf E. Leube
doaj +1 more source
Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy
eLife, 2021 Keratin intermediate filaments are an essential and major component of the cytoskeleton in epithelial cells. They form a stable yet dynamic filamentous network extending from the nucleus to the cell periphery, which provides resistance to mechanical ...
Miriam S Weber +5 more
doaj +1 more source
Role of Intermediate Filaments in Vesicular Traffic
Cells, 2016 Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells.
Azzurra Margiotta, Cecilia Bucci
doaj +1 more source
Ndel1 promotes axon regeneration via intermediate filaments. [PDF]
PLoS ONE, 2008 Failure of axons to regenerate following acute or chronic neuronal injury is attributed to both the inhibitory glial environment and deficient intrinsic ability to re-grow. However, the underlying mechanisms of the latter remain unclear.
Cory Toth +9 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2021 Cytoskeletal filaments are structures of utmost importance to biological cells and organisms due to their versatility and the significant functions they perform.
Bugra Özdemir, Ralf Reski
doaj +1 more source
Intermediate Filaments at the Junction of Mechanotransduction, Migration, and Development
Frontiers in Cell and Developmental Biology, 2017 Mechanically induced signal transduction has an essential role in development. Cells actively transduce and respond to mechanical signals and their internal architecture must manage the associated forces while also being dynamically responsive.
Rucha Sanghvi-Shah, Gregory F. Weber
doaj +1 more source
Intermediate filament structure
Bioscience Reports, 1985 In a previous communication (Biosci. Rep. 3, 517–525, 1993) we described quantitative X-ray diffraction studies of α-keratin which were shown to be consistent with the presence of finite arrays of repeating units, successive arrays being set down at axial intervals of 470 Å.
R D, Fraser, T P, MacRae
openaire +2 more sources
History and phylogeny of intermediate filaments: Now in insects
BMC Biology, 2011 Intermediate filaments include the nuclear lamins, which are universal in metazoans, and the cytoplasmic intermediate filaments, which are much more varied and form cell type-specific networks in animal cells.
Strelkov Sergei V, Herrmann Harald
doaj +1 more source
Lens intermediate filaments [PDF]
Experimental Eye Research, 2009 The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates.
openaire +2 more sources
Epithelial Intermediate Filaments: Guardians against Microbial Infection?
Cells, 2016 Intermediate filaments are abundant cytoskeletal components of epithelial tissues. They have been implicated in overall stress protection. A hitherto poorly investigated area of research is the function of intermediate filaments as a barrier to microbial
Florian Geisler, Rudolf E. Leube
doaj +1 more source