Results 91 to 100 of about 57,607 (282)
PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping
Advanced Science, EarlyView.scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su +7 more
wiley +1 more source
Molecular Brain, 2009 Summary The anterior cingulate cortex (ACC) is involved in sensory, cognitive, and executive functions. Studies of synaptic transmission and plasticity in the ACC provide an understanding of basic cellular and molecular mechanisms for brain functions ...
Wu Long-Jun +4 more
doaj +1 more source
Spiking Dynamics during Perceptual Grouping in the Laminar Circuits of Visual Cortex [PDF]
, 2009 Grouping of collinear boundary contours is a fundamental process during visual perception. Illusory contour completion vividly illustrates how stable perceptual boundaries interpolate between pairs of contour inducers, but do not extrapolate from a ...
Grossberg, Stephen +2 more
core +1 more source
Organic Thin‐Film Transistors for Neuromorphic Computing
Advanced Electronic Materials, EarlyView.Organic thin‐film transistors (OTFTs) are reviewed for neuromorphic computing applications, highlighting their power‐efficient, and biological time‐scale operation. This article surveys OFET and OECT devices, compares them with memristors and CMOS, analyzes how fabrication parameters shape spike‐based metrics, proposes standardized characterization ...
Luke McCarthy +2 more
wiley +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.Musculoskeletal humanoids exhibit rich biomechanical properties that remain insufficiently unified in prior discussions. This article systematically categorizes muscle characteristics into five properties: redundancy, independency, anisotropy, variable moment arm, and nonlinear elasticity, and analyzes their combined effects on control.
Kento Kawaharazuka +2 more
wiley +1 more source
Neurobiology of DiseaseAlthough early telencephalic interneuron dysfunction in animal models and cortical interneuron deficits in Huntington's disease (HD) have been documented, their developmental origins and causal contributions to disease pathogenesis remain incompletely ...
Aldrin E. Molero +6 more
doaj +1 more source
Stem Cell Reports, 2019 Summary: Striatal interneurons are born in the medial and caudal ganglionic eminences (MGE and CGE) and play an important role in human striatal function and dysfunction in Huntington's disease and dystonia.
Zoe Noakes +7 more
doaj +1 more source
Mechanistic Information and Causal Continuity [PDF]
, 2010 Some biological processes (our examples are DNA expression and a reflex response in the leech) move from step to step in a way that cannot be completely understood solely in terms of causes and correlations.
Bogen, Jim, Machamer, Peter
core
Advanced Intelligent Systems, EarlyView.This article presents a nonplanar niobium oxide (NbOx) neuron device fabricated using an atomic layer deposition (ALD) method for use in oscillatory neural networks (ONNs). Potentially, such nonplanar geometry allows for high‐density arrays. The desired threshold switching (TS) characteristics are achieved through an interfacial method using a thin ...
Jaehyun Moon +6 more
wiley +1 more source