Results 111 to 120 of about 145,959 (288)
The 9th International RASopathies Symposium
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson +1 more
wiley +1 more source
Cortical and Striatal Circuits in Huntington's Disease
, 2020 Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
core +1 more source
Reticulospinal inhibition of interneurones
The Journal of Physiology, 1968 1. The effect of electrical stimulation of the brain stem on interneurones in the dorsal horn and intermediary region has been investigated in decerebrate cats after partial transection of the spinal cord.2. Stimuli that effectively depress reflex transmission without giving a primary afferent depolarization inhibit the discharge evoked from the flexor
I, Engberg, A, Lundberg, R W, Ryall
openaire +3 more sources
Functional Segregation of Epileptogenicity within the Human Amygdala
Annals of Neurology, EarlyView.Objective In temporal lobe epilepsy (TLE), the amygdala in the epileptogenic network is underestimated compared to other regions such as the hippocampus. Recent advances in anatomical neuroimaging and stereoelectroencephalography (SEEG) signal analyses could help better understand the involvement of the different amygdala nuclei in the genesis of ...
Odile Feys +14 more
wiley +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2007 Introducción. Algunos signos clínicos de la rabia y estudios experimentales previos sugieren que esta infección viral podría afectar al sistema GABAérgico. Objetivo. Evaluar el efecto de la infección con el virus de la rabia sobre la expresión de GABA en
Aura Caterine Rengifo +1 more
doaj +1 more source
Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders
Advanced NanoBiomed Research, EarlyView.This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng +9 more
wiley +1 more source
Hominoid‐specific calretinin‐immunopositivity of the optic radiation (geniculocalcarine tract)
The Anatomical Record, EarlyView.Calretinin‐immunostained coronal section through the primary (V1) and extrastriate (ExSt) cortex of the lar gibbon. Note that the optic radiation (OR) is strongly calretinin‐immunoreactive. This calretinin‐immunopositivity of the OR distinguishes the Hominoidea from other primates in terms of the neurochemistry of the OR.
Nelyane N. M. Santana +5 more
wiley +1 more source
Frontiers in Cellular NeuroscienceParvalbumin (PV) interneurons in the dorsal striatum (DS) are fast-spiking GABAergic cells critical for feedforward inhibition and synaptic integration within basal ganglia circuits.
Claire Naon +18 more
doaj +1 more source
Computational Pattern Separation Models of Dentate Gyrus Neural Subpopulation in the Hippocampus
Caspian Journal of Neurological Sciences, 2022 Hippocampus is a part of the brain that has an essential role in memory and learning. It is involved in many cognitive and behavioral phenomena, including the pattern separation process: the ability to distinguish patterns with very high similarity.
Nazal Modhej +3 more
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