Results 211 to 220 of about 176,830 (333)
Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava +9 more
wiley +1 more source
Distinct Activity Profiles of Somatostatin-Expressing Interneurons in the Neocortex
Srikanth Ramaswamy +2 more
doaj +1 more source
Gpr176 modulates the firing pattern of parvalbumin-positive interneurons in the orbitofrontal cortex of mouse. [PDF]
Tian J, Huang Z, Zhang W.
europepmc +1 more source
This multicenter retrospective study evaluated the use of intravenous immunoglobulin (IVIG) in 14 children with Dravet syndrome as a preventive strategy against febrile status epilepticus. Over a 6‐month period, IVIG was associated with a significant reduction in hospitalizations for febrile status epilepticus.
Romane Marc +9 more
wiley +1 more source
Cerebellar climbing fibers impact experience-dependent plasticity in the mouse primary somatosensory cortex. [PDF]
Silbaugh A, Koster KP, Hansel C.
europepmc +1 more source
Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function
Hua Hu, J. Gan, P. Jonas
semanticscholar +1 more source
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim +6 more
wiley +1 more source
3-Nitrotyrosine activates excitatory interneurons by inhibiting GABA receptors in the rat spinal dorsal horn. [PDF]
Kaimochi Y +9 more
europepmc +1 more source
Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong +5 more
wiley +1 more source

