Results 231 to 240 of about 118,802 (309)

Dentate gyrus network regulation by somatostatin- and parvalbumin-expressing interneurons differentially impacts spatial memory processing. [PDF]

iScience
Raven F, Vankampen AA, He A, Aton SJ.
europepmc   +1 more source

Early Isoflurane Exposure Is Associated With Delayed Adolescent Neurobehavioral Deficits, Accompanied by Dysregulation of FOXG1 and EB3

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Early‐life exposure to general anesthetics has been linked to long‐term neurodevelopmental risks, yet the underlying mechanisms remain unclear. Using a mouse model, we show that neonatal isoflurane exposure at Postnatal Day 7 leads to age‐dependent behavioral alterations, changes in cortical neuronal abundance and layer‐specific neuronal ...
Ke Chen, Mengdi Xia, Changhong Li, Zhenhua Ren, Xiaohui Li   +4 more
wiley   +1 more source

Feature-tuned excitation of somatostatin interneurons drives figure-ground segregation. [PDF]

Neuron
Zhang YE, Tao HW.
europepmc   +1 more source

Neurodevelopmental Consequences Induced by Early‐Life Lead Exposure Through Disruption of Neurotransmitter Pathways and Molecular Mechanisms: A Systematic Review

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha, Aluru Parithathvi, Kamalesh Dattaram Mumbrekar, Herman Sunil Dsouza   +3 more
wiley   +1 more source

Fast Spiking Interneurons Autonomously Generate Fast Gamma Oscillations in the Medial Entorhinal Cortex with Excitation Strength Tuning ING-PING Transitions. [PDF]

eNeuro
Williams B, Vedururu Srinivas A, Baravalle R, Fernandez FR, Canavier CC, White JA.   +5 more
europepmc   +1 more source

Test–Retest Reliability of Sensorimotor Activity Measured With Spinal Cord fMRI

Human Brain Mapping, Volume 47, Issue 10, July 2026.
fMRI captured sensorimotor activation in hand‐related spinal cord regions, in accord with the established neuroanatomical organisation of the cord. While task performance reliability was good‐to‐excellent, the reliability of spinal cord activation was mixed.
Olivia S. Kowalczyk, Sonia Medina, Alessandra Venezia, Dimitra Tsivaka, Aminul I. Ahmed, Steven C. R. Williams, Jonathan C. W. Brooks, David J. Lythgoe, Matthew A. Howard   +8 more
wiley   +1 more source

Selective Lis1 inactivation disrupts migration and positioning of cortical somatostatin interneurons. [PDF]

Sci Rep
Pombero A, García-López R, Geijo-Barrientos E, Martínez S.   +3 more
europepmc   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

MedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu, Xinyan Wu, Ting Yin, Feining Huang, Manqi Kong, Yu Yang, Zinan Liu, Jiabin Yu, Tianpeng Zhang   +8 more
wiley   +1 more source

Subthreshold Kir and I_h currents modulate excitability of layer 1 VIP interneurons in the medial prefrontal cortex. [PDF]

Biol Res
Moreno C, Riquelme D, Cornejo C, Leyton P, Leiva-Salcedo E.   +4 more
europepmc   +1 more source

Dexmedetomidine Rapidly Relieves Stress‐Induced Hyperalgesia via Presynaptic α2‐Adrenergic Inhibition at Orbitofrontal–Insular Glutamatergic Synapses

MedComm, Volume 7, Issue 7, July 2026.
This study identified a maladaptive OFC–AIC glutamatergic circuit in stress‐induced hyperalgesia induction. This critical circuit provides an α2‐AR‐dependent braking target for dexmedetomidine to alleviate excessive glutamatergic transmission and hyperalgesia. ABSTRACT Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, is widely used for
Hui Rong, Yang‐Xun Zhang, Huijie Zhu, Yinyao Li, Yunfan Hou, Yun‐Yong Xie, Lu‐Yao Li, Bei‐Bei Zhang, Shu‐Tao Xie, Wei Zhang, Qi‐Peng Zhang, Xiao‐Yang Zhang, Jing‐Ning Zhu, Xiaoping Gu, Zhengliang Ma   +14 more
wiley   +1 more source