Results 281 to 290 of about 176,830 (333)

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, Volume 600, Issue 3, Page 342-355, February 2026.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Prefrontal gamma oscillations and fear extinction learning require early postnatal interneuron-oligodendroglia communication. [PDF]

Nat Commun
Plaisier F, Ibaceta-González C, Khelfaoui H, Watson AES, Poilbout C, Voronova A, Angulo MC.   +6 more
europepmc   +1 more source

Synaptic transmission in supragranular layers of the human cortex - comparative review of structure, function, and plasticity. [PDF]

Front Synaptic Neurosci
Eichler A, Kruse P, Schob C, Lenz M.
europepmc   +1 more source

Transient juvenile demyelination impairs maturation and function of parvalbumin-positive interneurons in the prefrontal cortex. [PDF]

PLoS Biol
Hijazi S, Pascual-García M, Nabawi Y, Kushner SA.   +3 more
europepmc   +1 more source

Architecture and cellular composition of focal cortical dysplasia type II: qualitative review of histological studies. [PDF]

Front Cell Neurosci
Castaño-Martín R, Metais A, Ciura S, Blauwblomme T.   +3 more
europepmc   +1 more source

Autapses enable temporal pattern recognition in spiking neural networks. [PDF]

PLoS One
Yaqoob M, Steuber V, Wróbel B.
europepmc   +1 more source

Developmental and early-life stress-induced effects on 5-HT₃R-expressing interneurons within auditory cortex. [PDF]

Neurobiol Stress
Moore JT, Sunthimer MJ, White E, Mellott JG, Rosen MJ.   +4 more
europepmc   +1 more source

NDNF+ interneurons have a privileged role in regulating cortical excitability

Richardson A, Mercier MS, Shimoda Y, Graham RT, Leite M, Garcia A, Muller M, Bond SA, Grozdanova M, Wu Q, Lieb A, Kullmann DM, Magloire V.   +12 more
europepmc   +1 more source